A comparison of regional cerebral blood flow measurements made with betaand gamma-emitting isotopes revealed good correspondence in areas of normal perfusion and reactive hyperemia but poor correspondence in areas of focal ischemia. After middle cerebral artery occlusion at normocapnia, there was a 65% reduction in regional cerebral blood flow from 1.40 ± 0.27 ml/g min~' to 0.49 ± 0.10 ml/g min...

A comparison of regional cerebral blood flow measurements made with betaand gamma-emitting isotopes revealed good correspondence in areas of normal perfusion and reactive hyperemia but poor correspondence in areas of focal ischemia. After middle cerebral artery occlusion at normocapnia, there was a 65% reduction in regional cerebral blood flow from 1.40 ± 0.27 ml/g min~' to 0.49 ± 0.10 ml/g min...

A highly reliable model for the study of focal cerebral ischemia has been developed using a retro-orbital approach to occlude the lateral lenticulostriate arteries of the baboon. An infarction of the caudate, putamen and the anterior limb of the internal capsule has consistently been produced. Reliability has been attained because the anatomical variations of the lenticulostriate arteries of ea...

The effectiveness and efficacy of hyperbaric oxygen (HBO) preconditioning and post-treatment modalities have been demonstrated in experimental models of ischemic cerebrovascular diseases, including global brain ischemia, transient focal and permanent focal cerebral ischemia, and experimental neonatal hypoxia-ischemia encephalopathy. In general, early and repetitive post-treatment of HBO appears...