Background—The relationship between impaired brachial flow-mediated dilation (FMD) and subsequent clinical cardiovascular events is not well established, especially in older adults whose FMD is often diminished. We assessed the hypothesis that FMD predicts incident cardiovascular events in a population-based cohort of older adults. Methods and Results—FMD was measured at the 1997 to 1998 Cardio...

Foot-and-mouth disease (FMD) is a contagious viral disease of cloven-footed animals. It is endemic in Pakistan with huge economic losses. The aim of the study was to estimate the sero-prevalence of FMD in small ruminants (sheep and goats) kept in proximity to large ruminants with a recent history of FMD outbreak. The study was conducted in seven purposively selected districts of Pakistan. A tot...

A case-control study was conducted to identify herd-level risk factors associated with foot-and-mouth disease (FMD) in Ecuador. Case herds were those with presence of cattle with clinical signs of FMD and that tested positive for FMD virus during the epidemic of 2002 (n = 39). Control farms (n = 78) were selected randomly from a list of farms without a history of FMD. All study farms were visit...

Foot-and-mouth disease (FMD) is one of the most devastating diseases of livestock (1). The disease is caused by infection with a picornavirus, generically referred as FMD virus (FMDV), which is considered one of the most infectious agents affecting animals (2). FMD status affects national and international movement and trade of animals and animal products, and food animal trade is expected to p...

Foot-and-Mouth Disease (FMD) is a clinical syndrome in animals due to FMD virus that exists in seven serotypes, whereby recovery from one sero-type does not confer immunity against the other six. So when considering intervention strategies in endemic settings, it is important to take account of the characteristics of the different serotypes in different ecological systems. FMD serotypes are not...

Studies have demonstrated that the acute administration of 3-hydroxy-3 methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors has protective effects in the setting of ischemia-reperfusion (IR). Previously, we demonstrated that a single dose of rosuvastatin prevented IR-induced endothelial dysfunction in humans through a cyclooxygenase-2-dependent mechanism. Whether the chronic administration ...

Inhibition of a sympathetic stimulus (i.e., sympatholysis) during forearm exercise is reduced with age in women. This age-related alteration has not been characterized in the lower extremity vasculature of women, and the potential for blunting of the conduit artery dilatory response to a sudden increase in shear stress [flow-mediated dilation (FMD)] has not been examined in older adults of eith...

This study deals with the transport behavior of the coarse-sediment at Masudagawa flood mitigation dam (FMD), Japan. Radio frequency identification system (RFID) was used to trace the displacement of the IC tagged particles following major flood events since June 2011. Through this, the relationship between recovery rate of the tagged particles and distribution of shear stress over the FMD bed ...

Abstract : Foot and Mouth Disease is one of  the important live stocks contagious viral disease caused by Aphtovirus genus ,  that is belong to family RNA virus  picornaviride. The important characteristic of FMD virus is high mutation that give rise to diversity of Antigen in surface of Neutralizing proteins. For this reason FMD virus have 7 distinct serotype and many subtype. Vaccination is o...

Background: Foot-and-mouth disease (FMD) is a highly contagious and economically important disease that affects cloven-hoofed animals worldwide. In recent years, a series of outbreaks of FMD have occurred in many countries. Recombinant protein synthesis incorporating protective B- and T-cell epitopes are candidates for new safer and more effective (FMD) vaccines that have potential to provide p...