The 1,2-dicarbonyl compounds 3-deoxyglucosulose (3-DG), glyoxal (GO), and methylglyoxal (MGO) were measured as the corresponding quinoxalines after derivatization with orthophenylendiamine using RP-HPLC and UV-detection in commercially available honey samples. Whereas for most of the samples values for 3-DG, MGO, and GO were comparable to previously published data, for six samples of New Zealan...

Methylglyoxal (MGO), an active metabolite of glucose, has been reported to induce vascular cell apoptosis in diabetic complication. Polydatin (PD), a small natural compound from Polygonum cuspidatum, has a number of biological functions, such as antioxidative, anti-inflammatory, and nephroprotective properties. However, the protective effects of PD on MGO-induced apoptosis in endothelial cells ...

Heterostructures and interfacial defects in a 40-nm-thick SrTiO(3) (STO) film grown epitaxially on a single-crystal MgO (001) were investigated using aberration-corrected scanning transmission electron microscopy and geometric phase analysis. The interface of STO/MgO was found to be of the typical domain-matching epitaxy with a misfit dislocation network having a Burgers vector of ½ a(STO) <100...

We report a hydrothermal synthesis method for MgO shell coatings directly onto the surface of ZnO nanowire arrays. The entire process can be carried out below 100 °C. The MgO shells are produced by the addition of 10 mM magnesium nitrate with 0.2 M sodium hydroxide in water, resulting in a shell thickness of up to 8 nm, verified by high resolution transmission electron microscopy. The viability...

Composite (La0.67Ca0.33MnO3)12x :(MgO)x films were prepared by metalorganic aerosol deposition on a ~100!MgO substrate for different concentrations of the ~MgO! phase (0<x<0.8). At x'0.3 a percolation threshold in conductivity is reached, at which an infinite insulating MgO cluster forms around the La0.67Ca0.33MnO3 grains. This yields a drastic increase of the electrical resistance for films wi...

All refractory, NbN/MgO/NbN (superconductor-insulator-superconductor) tunnel junctions have been fabricated by in situ sputter deposition. The influence ofMgO thickness (0.8-6.0 nm) deposited under different sputtering ambients at various deposition rates on current-voltage (IV) characteristics of small-area ( 30 X 30 pm) tunnel junctions is studied. The NbN/MgO/NbN trilayer is deposited in sit...

Background The contribution of methylglyoxal (MGO) and soluble receptor for advanced glycation end products (sRAGE) in the presence of rheumatoid arthritis (RA) is still unknown. We investigated whether serum MGO and sRAGE were related to the presence of disease activity in RA. Methods 80 patients with RA and 30 control subjects were included in a cross-sectional study. The severity of RA was...

Shock-compressed MgO radiates thermally at temperatures between 2900 and 3700 K in the 170-200 GPa pressure range. A simple energy-transport model of the shocked-MgO-targets distinguishes between different shock-induced radiation sources in these targets and provides estimates of spectral absorption-coefficients, ahM for shocked MgO (e.g. at 203 GPa, a h M g O 630, 7500, 4200 and 3800 m-’, a t ...

This study examined the effect of methylglyoxal (MGO)-derived nonenzymatic posttranslational modifications (nePTMs) on the binding affinity of S100A12 to its natural receptor for advanced glycation end-products (RAGE). Binding of MGO-modified S100A12 to RAGE decreased significantly with increasing MGO concentration and incubation time. Ca(2+)-induced S100A12 hexamerization was impaired only at ...

Some insights into the origin of cratonic mantle can be gained from “eclogite” (loosely defined here as an assemblage containing garnet and any pyroxene) xenoliths hosted in kimberlites erupted through Archean (~2.5­3.5 Gy) cratons. One subset of Archean eclogite xenoliths, the low MgO Archean xenoliths, is presently believed to represent metamorphosed fragments of ancient altered oceanic crust...