This study was conducted to determine the location of DNA segment with homology to the rat conserved genomic DNA in human chromosomes. The labeled rat genomic DNA was hybridized with normal human (male) metaphases. The study of 74 metaphases after fluorescence in situ hybridization showed 371 twin-spot signals on human chromosomes. Statistical analysis indicated that the specific accumulation o...

Background A decrease in aneuploidy rate following a prolonged co-culture of human blastocysts has been reported. As co-culture is not routinely used in assisted reproductive technology, the present study aimed to evaluate the effect of the prolonged single culture on the rate of diploid cells in human embryos with aneuploidies. MaterialsAndMethods In this cohort study, we used fluorescence in ...

conventional cytogenetic is the standard technique for detection of philadelphia (ph) chromosome in chronic myeloid leukemia (cml). evaluation of abelson murine leukemia/breakpoint cluster region (abl/bcr) fusion using dual-colour fluorescence in situ hybridization (d-fish) is an alternative approach allowing rapid and reliable detection of the disease. we employed the technique of interphase d...

The importance of cancer biomarkers is now increasingly recognized and acted on by regulatory organizations, healthcare providers (from reimbursement through to practicing clinicians), cancer organizations, research institutes, and charities. For example, the American Joint Committee on Cancer (AJCC) states in the opening of its mission statement, “The purpose and scope of the AJCC is to create...

this study was conducted to determine the location of dna segment with homology to the rat conserved genomic dna in human chromosomes. the labeled rat genomic dna was hybridized with normal human (male) metaphases. the study of 74 metaphases after fluorescence in situ hybridization showed 371 twin-spot signals on human chromosomes. statistical analysis indicated that the specific accumulation o...