INTRODUCTION Extracorporeal membrane oxygenation (ECMO) is used in critically ill patients presenting acute cardiac and/or pulmonary dysfunctions, who are at high risk of developing acute kidney injury and fluid overload. Continuous renal replacement therapy (CRRT) is commonly used in intensive care units (ICU) to provide renal replacement and fluid management. We conducted a review to assess t...

Background: Very preterm birth often results in the development of bronchopulmonary dysplasia (BPD) with an inverse correlation gestational age and birthweight. This very population is especially exposed to interventions, which affect BPD. Objective: The goal our review summarize evidence on these daily procedures provide evidence-based recommendations for management Methods: We conducted a sys...

Fluid resuscitation with colloids is an established second line therapy for septic patients. Evidence of relative efficacy outcomes is tempered by considerations of the relative costs of the individual fluids. An assessment of recent large clinical trials was performed, resulting in a ranking in the efficacy of these therapies. Probabilities for mortality and the need for renal replacement ther...

Appropriate use of fluid infusion in cardiac surgery patients is of primary importance in the perioperative period in order to optimize cardiac output and oxygen delivery and to reduce the use of vaspressors and inotropes. Fluid infusion is usually triggered by arterial hypotension, low urine output and signs of inadequate tissue oxygenation (e.g. hyperlactatemia). This general rule, however, m...

BACKGROUND 0.9% sodium chloride (saline) is the most commonly administered resuscitation fluid on a global basis but emerging evidence suggests that its high chloride content may have important adverse effects. OBJECTIVE To describe the study protocol for the Plasma- Lyte 148 v Saline study, which will test the hypothesis that in critically ill adult patients the use of Plasma-Lyte 148 (a buf...

The use of intravenous fluids is routine in patients undergoing surgery or critical illness; however, controversy still exists regarding optimum fluid therapy. Recent literature has examined the effects of different types, doses, and timing of intravenous fluid therapy. Each of these factors may influence patient outcomes. Crystalloids consist of isotonic saline or balanced electrolyte solution...

Intensive care unit and surgical populations are at increased risk for acute kidney injury (AKI) and oliguria, which often lead to fluid accumulation. Volume resuscitation is a cornerstone in the treatment of hemodynamic instability in these populations. However, fluid balance evaluation and its management in the critically ill can be challenging. Several clinical and paraclinical tools may aid...