In 20 unanesthetized sheep, we measured lung lymph flow and lymph and plasma protein concentrations during steady-state base-line conditions and during steady-state elevations of pulmonary microvascular hydrostatic pressure (range 3 to 23 cm H2O). In every sheep there was a base-line lung lymph flow (average 5.7 +/- 2.5 (SD) ml/hour), demonstrating that net fluid filtration occurred. The base-l...

Microvascular fluid exchange (flow J(v)) underlies plasma/interstitial fluid (ISF) balance and oedematous swelling. The traditional form of Starling's principle has to be modified in light of insights into the role of ISF pressures and the recognition of the glycocalyx as the semipermeable layer of endothelium. Sum-of-forces evidence and direct observations show that microvascular absorption is...

PURPOSE To investigate the osmotic water permeability of lacrimal gland (LG) duct epithelium by means of calculation of filtration permeability and to investigate LG ductal fluid secretion. METHODS Experiments were performed on isolated rabbit LG duct segments maintained in short-term culture. Osmotically determined fluid movement or fluid secretion into the closed intraluminal space of cultu...

The filtration of fluid in 2D porous medium is simulated by the molecular dynamics technique. The high concentration of fluid is created at the initial point in time and the number of fluid particles is investigated in all porous. The concentration of particles pores and parameters of interaction potentials is varied. In all cases the particles concentration decay is well described by exponenti...

In this paper, we characterize the filtration and deposition profiles of a recombinant analog of Norwalk virus, an important waterborne pathogen, in packed beds of saturated quartz sand under both ‘clean-bed’ and ‘dirty-bed’ conditions. Under clean-bed conditions with NaCl as the electrolyte, the retained Norwalk virus particles decline like a power-law with depth. The power-law decay in retain...

In this paper, we consider a vertically positioned cylindrical filtering element. Filtering occurs in the radial direction, therefore, direction of velocities liquid and suspended particles coincide with direction. The flow can be considered to one-dimensional radially axisymmetric. To describe such process, axisymmetric Stefan problem will formulated. mass balance formalism Darcy’s law are uti...

P ulmonary microembolism is associated with the generation of prostaglandin thromboxanes.’ Since pulmonary microembolism also causes lung edema, the generation of these arachidonic acid products may contribute to extravascular fluid accumulation in the lung. Thromboxane A, (TxA,) is a particularly vasoactive substance in the pulmonary circulation since infusion of the cyclic endoperoxide analog...