The tissue microenvironment has profound effects on tissue-specific regeneration. The 3-dimensional extracellular matrix (ECM) niche influences the linage-specific differentiation of stem cells in tissue. To understand how ECM guides tissue-specific regeneration, we established a series of 3D composite scaffolds containing ECMs derived from different primary cells isolated from a single animal ...

The purpose of this study was to investigate the radiation attenuation effect due reflection and refraction that occurs when passes through composite material simulation. gamma-ray shielding ability composites with different structures, such as layered composite, fibrous particle-added composites, compared. For regardless thickness, structure could not be seen. simulated coefficient found than ...

A novel porous composite material composed of hydroxyapatite, poly(vinyl alcohol) (PVA), and gelatin (Gel) was fabricated by emulsification. Scanning electron microscopy showed that the material had a well-interconnected porous structure including many macropores (100-500 microm) and micropores (less than 20 microm) on their walls. The composite had a porosity of 78% and showed high water absor...

Fibrous networks of biopolymers possess unique properties: mechanical stability at low concentrations, an extremely porous architecture, and strong stiffening small deformations. An outstanding challenge is to find methods that allow tailor the properties these bionetworks or their synthetic equivalents without changing polymer concentration, which simultaneously changes all other hydrogel prop...

Electrospun micro- and nanofibrous poly(glycerol sebacate)-poly(ε-caprolactone) (PGS-PCL) substrates have been extensively used as scaffolds for engineered tissues due to their desirable mechanical properties and their tunable degradability. In this study, we fabricated micro/nanofibrous scaffolds from a PGS-PCL composite using a standard electrospinning approach and then coated them with silve...

The aim of this study was to achieve on-demand controlled drug release from the dual-drug-loaded poly(lactic-co-glycolic acid)/mesoporous silica nanoparticles electrospun composite fibers by the application of ultrasound irradiation. Two drugs were loaded in different part of the composite fibrous materials, and it was found that ultrasound as an external stimulus was able to control release of...

The electrospinning technique is a versatile method for the production of fibrous scaffolds able to resemble the morphology of the native extra cellular matrix. In the present paper, electrospinning is used to fabricate novel SiO2 particles (type MCM-41) containing poly(epsilon-caprolactone) (PCL) fibers. The main aims of the present work are both the optimization of the particle synthesis and ...

Any consideration of the durability of the high performance composite materials and structural adhesives used in aerospace construction must recognize that these are brittle materials and that their failure mode is characterized by flaw growth and propagation. One can easily anticipate a variety of flaws and defects; surface cuts, internal cracks due to stress relief and deliberate holes cut fo...

A superfine Li0.33La0.557TiO₃ (LLTO, 69.4 nm) was successfully synthesized by a facile solvent-thermal method to enhance the electrochemical properties of the lithium-ion battery separator. Co-axial nanofiber of cellulose and Poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP) was prepared by a co-axial electrospinning technique, in which the shell material was PVDF-HFP and the core was...