BACKGROUND Hemorrhage from the left ventricle can be critical and sutureless repair using a fibrin-based haemostat (TachoComb) is one effective option. When active hemorrhage is not controlled by the haemostat, we have used a polyglycolic acid (PGA) sheet and fibrin glue in addition. Here we investigated whether the PGA sheet and fibrin glue combined with TachoComb had stronger adhesive propert...

OBJECTIVE Pleurodesis using chemical agents has been applied to high-risk patients with pneumothorax. This treatment, however, is sometimes unsuccessful in patients with intractable pneumothorax. We have developed intrapleural administration of diluted fibrin glue as an effective treatment for such patients. METHODS Fibrin glue was diluted 4-fold with saline and/or contrast media. Pleurodesis...

The hydrogel synthesized from biocompatible polyaspartamide, and oxidized dextran had stronger adhesion properties when tested on porcine skin than the commercially available fibrin glue.

PURPOSE To evaluate whether fibrin glue causes less postoperative pain, discomfort and work inaptitude in conjunctival closure following 20 gauge pars plana vitrectomy than sutures. DESIGN Retrospective study. METHODS A questionnaire was sent in 2006 to 506 patients who underwent 20 gauge pars plana vitrectomy in 2004 at the University Hospital, Leuven, Belgium. Patients were asked about th...

Objective: A systematic review of randomized controlled trials (RCTs) and non-RCTs was performed to evaluate the efficacy and safety of reducing blood loss using fibrin glue and tranexamic acid in patients who underwent total knee arthroplasty (TKA). Method: Relevant randomized controlled trial (RCTs) and non-RCT literature dealing with fibrin glue and tranexamic acid in TKA for reducing total ...

Background and Objectives. This study was designed to determine the effectiveness of fibrin glue plus conventional drain placement versus conventional drain placement in the prevention of seromas after breast procedures. Among methods employed to reduce seroma magnitude and duration, fibrin glue has been proposed in numerous studies, with controversial results. Design and Setting. A prospective...

Objective: To compare the tensile strength of fibrin glue, 2-octyl cyanoacrylate, and liquid ocular bandage to conventional nylon 10-0 sutures in sealing central linear corneal lacerations. Methods: An experimental in-vitro study was performed on 74 porcine eyes. A 27-gauge needle connected to an infusion system with balanced salt solution was inserted into the anterior chamber and the bottle h...

PURPOSE To compare clinical parameters and the tear levels of inflammatory cytokines between pterygium surgery using sutures or fibrin glue. METHODS Fifty-six patients with primary pterygium were divided into the suture group and the glue group, in which the autograft was secured with 10-0 Vicryl sutures and fibrin glue, respectively. A questionnaire, slit-lamp examination, Schirmer test, and...