MOTIVATION Of the approximately 200 proteins that have been identified for the vaccinia virus (VACV) genome, many are currently listed as having an unknown function, and seven of these are also found in all other poxvirus genomes that have been sequenced. The G5R protein of VACV is included in this list, and to date, very little is known about this essential and highly conserved protein. Conven...

Wetlands represent sources or sinks of the greenhouse gas nitrous oxide (N2O). The acidic fen Schlöppnerbrunnen emits denitrification derived N2O and is also capable of N2O consumption. Global warming is predicted to cause more extreme weather events in future years, including prolonged drought periods as well as heavy rainfall events, which may result in flooding. Thus, the effects of prolonge...

background: perforin is known to be important in cytolytic activity mediated by natural killer (nk) cells.   objective: to study the relationship between the efficiency of nk and lymphokine-activated killer (lak) cells activity, and the expression of perforin and hla class i molecules.   methods: lak cells were generated by in vitro culturing of human peripheral blood lymphocytes (pbls) in the ...

Measuring Responsiveness in the Therapeutic Relationship: A Patient Perspective Harry T. Reis , Margaret S. Clark , Denis J. Pereira Gray , Fen-Fang Tsai , Judith B. Brown , Moira Stewart & Lynn G. Underwood To cite this article: Harry T. Reis , Margaret S. Clark , Denis J. Pereira Gray , Fen-Fang Tsai , Judith B. Brown , Moira Stewart & Lynn G. Underwood (2008) Measuring Responsiveness in the ...

The catalytic activity and amino acid specificity of the tomato Pto and Fen kinases were investigated. The Pto and Fen genes were fused to the carboxyl terminus of the maltose-binding protein and expressed in Escbericbia coli. lncubation of the purified fusion proteins with [y-3ZP]ATP in an in vitro assay showed that both proteins were capable of autophosphorylation. Mutant fusion proteins in w...

Predicted daily fluxes from an ecosystem model for water, carbon dioxide, and methane were compared with 1994 and 1996 Boreal Ecosystem–Atmosphere Study (BOREAS) field measurements at sites dominated by old black spruce (Picea mariana (Mill.) BSP) (OBS) and boreal fen vegetation near Thompson, Man. Model settings for simulating daily changes in water table depth (WTD) for both sites were design...

TO THE EDITOR—The report on the intrinsic antimycobacterial activity of ibupro-fen and low-dose aspirin in a novel murine tuberculosis model is fascinating