The stimulatory effect of ferrous salts on the peroxidation of phospholipids can be enhanced by EDTA when the concentration of Fe2+ in the reaction is greater than that of EDTA. Hydroxyl-radical scavengers do not inhibit peroxidation until the concentrations of Fe2+ and EDTA in the reaction are equal. Lipid peroxidation is then substantially initiated by hydroxyl radicals derived from a Fenton-...

Bleomycin (BLM) is an anticancer antibiotic isolated from the supernatant of Streptomyces verticillus culture [21]. The cytotoxic activity of BLM depends on generation of singleand double-strand breaks in DNA (for review, see [16]). Indispensable for this BLM activity is the presence of metal ions, specifically Fe2+. Fe2+ BLM complexed with O2 or Fe 3+ BLM complexed with H2O2 leads to formation...

Nano-particles of polycrystalline Zn Fe2 O4 are prepared using sol-gel method with Ni, and Sm. They are obtained as dried gel after the successful chemical reaction of their respective metal nitrate solutions in the midst of citric acid as catalyst. Synthesis of materials is confirmed using XRD from the report of single phase polycrystalline ferrite material. The magnetic properties of Zn-ferri...

The adsorption of Fe2+ by the manganese oxide coated zeolite (MOCZ) and iron oxide coated zeolite (FOCZ) was studied. Surface properties of adsorbents have been investigated for monitoring their changes and morphology for both of the MOCZ and FOCZ. Main variables namely; contact time, pH, initial concentration of Fe2+, size and dosage of adsorbent have been optimized, and the results contrasted...

The mechanism of the fluorescence quenching of aqueous thionine by various metal ions (Ce3+_, Fe2+, Mn2+, Mg2+, Cs+ and Na+) was studied at pn = 2.5. The following Stern-Volmer constants (K s v) were determined: XSv(Fe2+) == 1.13 dm3 mol -1 , Ksw(Mn2+) = 0.24 dm3 mol"1, Ksv(Ce3+) = 0.24 dm3 mol -1, i£sv(Cs~) — 0.03 dm3 mol -1 . At concentrations below 1 mol.dm -3 Na2S04 and MgS04 are very weak ...

Carbon dioxide adsorption isotherms have been computed for the Metal-Organic Framework (MOF) Fe2(dobdc), where dobdc4− = 2,5-dioxido-1,4-benzenedicarboxylate. A force field derived from quantummechanical calculations has been used to model adsorption isotherms within a MOF based on a parameterization scheme. Restricted Open-shell Møller-Plesset second-order perturbation theory (ROMP2) calculati...

Layered ƒÁ-titanium phosphate (ƒÁ-TiP), Ti(HP04)2.2H20, is well known as the host material of intercalation compounds and the inorganic ion-exchanger of H+/metal ion system. It was found to have high ion-exchange selectivity for Rb+ and Cs+ among alkali metal ions. The ionexchange reactions for these ions progressed in two steps according to pH. Part of water molecules in the mterlayer of ƒÁ-Ti...

Thermoplastic linear poly(ether-urethane) sulphonated ionomer (PEUSI), doped with natural Fe2+, was studied by Mössbauer spectroscopy at T = 78 and 290 K in order to monitor the chemical state of Fe species. The Fe2+ added was found to get only partly oxidised in the course of preparation of a dry polymer film from aqueous suspension. The oxidised part gave a ferric quadrupole doublet (over hal...

The first known magnetic mineral, magnetite, has unusual properties, which have fascinated mankind for centuries; it undergoes the Verwey transition around 120 K with an abrupt change in structure and electrical conductivity. The mechanism of the Verwey transition, however, remains contentious. Here we use resonant inelastic X-ray scattering over a wide temperature range across the Verwey trans...

Iron imbalance/accumulation has been implicated in oxidative injury associated with many degenerative diseases such as hereditary hemochromatosis, beta-thalassemia, and Friedreich's ataxia. Mitochondria are particularly sensitive to iron-induced oxidative stress - high loads of iron cause extensive lipid peroxidation and membrane permeabilization in isolated mitochondria. Here we detected and c...