BACKGROUND Fructose-1,6-diphosphate (FDP) is reported to have a salutary effect in endotoxin shock and sepsis. This investigation describes the effect of FDP on pulmonary and systemic hemodynamics, lung lymph protein clearance, and leukocyte count in sheep infused with Escherichia coli endotoxin. MATERIALS AND METHODS Anesthetized sheep (n = 18), some of which underwent thoracotomy to cannula...

BACKGROUND The exposome constitutes a promising framework to improve understanding of the effects of environmental exposures on health by explicitly considering multiple testing and avoiding selective reporting. However, exposome studies are challenged by the simultaneous consideration of many correlated exposures. OBJECTIVES We compared the performances of linear regression-based statistical...

AIM Psychophysical strategies designed for clinical visual field testing produce rapid estimates of threshold with relatively few stimulus presentations and so represent a trade-off between test quality and efficiency. The aim of this study was to determine the measurement error of a staircase algorithm similar to full threshold with standard automated perimetry (SAP) and frequency doubling per...

Using solid state radioimmunoassays developed by the first author, changes in the urine level of plasmin-like substances (PLS) and fibrin degradation products (FDP) before and after human kidney transplantation were determined in 49 transplant patients. Averages of urine PLS and FDP in a normal population of 51 persons were 0.13+/-0.10 (SD) and 0.14+/-0.07 microng/ml, respectively. In all trans...

Introduction Most humans have four lumbrical muscles in each hand numbered as first, second, third and fourth from the radial to ulnar side. Lumbrical muscles of the hand flex the second to fifth metacarpophalangeal joints and extend the interphalangeal joints of the fingers [1, 2]. The first and second lumbrical muscles originate from the radial side of the flexor digitorum profundus (FDP) ten...

avulsion injury of the flexor digitorum profundus (fdp) with concomitant fracture of the distal phalanx dorsal base is uncommon. simultaneous avulsion fractures of the insertion of this tendon associated with rupture of the tendon from the bony fragment and combination with dorsal base fracture is very rare and also complicated. a 36- year- old man fell and injured his right little finger. fdp ...