metastasis of gastroesphageal junction (gej) adenocarcinoma in skeletal muscle is rare and primary sites for skeletal muscle metastases are usually lung, renal and colorectal cancer. we have encountered with the first case report of solitary psoas muscle metastasis of gej adenocarcinoma. here we describe a 65 years old man was diagnosed with gej adenocarcinoma in tertiary hospital, tehran, iran...

BACKGROUND Exercise is one of the few treatments that provide significant improvements in chronic low back pain (CLBP). We developed an innovative exercise device for abdominal trunk muscles. This device can be used in a sitting or standing position and contains a built-in system to measure abdominal trunk muscle strength. We examined whether subjects can adequately use the device to perform th...

Received 10/7/2002; revised 10/30/2002; accepted 11/5/2002. For correspondence or reprints contact: Yen-Ling Chen, M.D., Department of Endocrinology and Metabolism, Shin Kong Wu Ho-Su Memorial Hospital. 95 Wen Chang Road, Shih Lin District, Taipei 111, Taiwan. Tel: (886)2-28332211 ext. 2032, Fax: (886)2-27044103, E-mail: [email protected] A 45-year-old woman complained of weakness, dizzines...

Inhibition of nitric oxide synthase (NOS) significantly attenuates the increase in skeletal muscle glucose uptake during contraction/exercise, and a greater attenuation is observed in individuals with Type 2 diabetes compared with healthy individuals. Therefore, NO appears to play an important role in mediating muscle glucose uptake during contraction. In this study, we investigated the involve...

Obesity is a major factor central to the development of insulin resistance and type 2 diabetes. The identification and characterization of genes involved in regulation of adiposity, insulin sensitivity, and glucose uptake are key to the design and development of new drug therapies for this disease. In this study, we show that the polarity kinase Par-1b/MARK2 is required for regulating glucose m...

The proinflammatory cytokine TNF-α is known to have a direct action on skeletal muscle in mammals. However, little is known regarding the potential effects of cytokines on nonimmune tissues, particularly in skeletal muscle, in fish. The aim of this study was to investigate the effects of recombinant trout TNF-α (rtTNF-α) on skeletal muscle carbohydrate metabolism in rainbow trout (Oncorhynchus ...

The "Splenocardiac Axis" describes an inflammatory signaling network underlying acute cardiac ischemia, characterized by sympathetic nerve stimulation of hematopoietic tissues, such as the bone marrow and spleen, which then release proinflammatory monocytes that populate atherosclerotic plaques, thereby promoting ischemic heart disease. Electronic (e) cigarettes, like tobacco cigarettes trigger...

objective(s): the ability to measure cellular proliferation non-invasively in renal cell carcinoma may allow prediction of tumour aggressiveness and response to therapy. the aim of this study was to evaluate the uptake of 18ffluorothymidine (flt) pet in renal cell carcinoma (rcc), and to compare this to 18f-fluorodeoxyglucose (fdg), and to an immunohistochemical measure of cellular proliferatio...

Methods A total of 123 patients who had baseline whole-body 18F-FDG PET/CT scans and underwent NACT followed by surgery for oesophageal cancer were included. Morphometric parameters including skeletal muscle density (SMD), skeletal muscle index, FM, FFM, FMR, VA/SA were measured and were correlated to clinical parameters, surgical findings and pathological chemotherapy response. The factors con...