Artocarpin, a natural prenylated flavonoid, has been shown to have various biological properties. However, its effects on human cutaneous squamous cell carcinoma (SCC) have not been previously investigated. We set out to determine whether artocarpin has cytotoxic effects on SCC cells and whether its pharmacological activity is dependent on protein-nutrient concentration. Our results showed that...

Combinations of fibroblasts (Fbs) and corresponding epithelial cells have been widely used in many tissues, such as the skin and breast tissues, to augment tissue repair and remodeling. Recently, a large amount of new data has indicated that nerve Fbs play critical roles in Schwann cells (SCs) and axons in vitro. However, little is known regarding the effects of co-transplanting nerve Fbs and S...

|We show that oversampled lter banks (FBs) offer more design freedom and less noise sensitivity than critically sampled FBs. We provide a parameterization of all synthesis FBs satisfying perfect reconstruction for a given oversampled analysis FB, and we derive bounds and expressions for the variance of the reconstruction error due to noisy subband signals. Finally, we introduce noise shaping in...

BACKGROUND Mesenchymal stromal cells (MSC) are increasingly investigated for their clinical utility in dogs. Fetal bovine serum (FBS) is a common culture supplement used for canine MSC expansion. However, FBS content is variable, its clinical use carries risk of an immune response, and its cost is increasing due to global demand. Platelet lysate (PL) has proven to be a suitable alternative to F...

Human dental pulp stem cells (hDPSCs), selected from the stromal-vascular fraction of dental pulp, are ecto-mesenchymal stem cells deriving from neural crests, successfully used in human bone tissue engineering. For their use in human therapy GMP procedures are required. For instance, the use of fetal bovine serum (FBS) is strongly discouraged in clinical practice due to its high risk of prions...

The cut-off criterion of serum levels of glycated hemoglobin (HbA1c) >6.5% as an alternative to fasting blood sugar (FBS) >7.0 mmol/L for diagnosis of diabetes mellitus still requires rigorous studies on diverse populations before its safe implementation. We conducted a regression analysis on 75 diabetic patients (40 males and 35 females) for testing the association between FBS and HbA1c and po...

BACKGROUND We examined fertility-specific distress (FSD) and general distress by type of fertility barrier (FB). METHODS In a random sample telephone survey, 580 US women reported their fertility intentions and histories. Six groups of women were identified: (i) no FBs, (ii) infertile with intent, (iii) infertile without intent, (iv) other fertility problems, (v) miscarriages and (vi) situati...

We show that oversampled filter banks FBs) offer more design freedom and less noise sensitivity t 6 an critically sampled FBs. We provide a parameterization of all synthesis FBs satisfyin perfect reconstruction for a given oversampled analysis FE, and we derive bounds and expressions for the variance of the reconstruction error due to noisy subband signals. Finally, we introduce noise shaping i...

BACKGROUND Diabetes is undoubtedly one of the most challenging health problems in 21st century. Understanding the pathogenesis and preventing long term complications have been major goals of research in diabetes mellitus (DM). Research in the past few years has linked oxidative stress and inflammation to beta cell dysfunction. Aim of this study is to evaluate serum gamma-glutamyl transferase (G...

abstract objective: diabetes mellitus is the most common metabolic disease. one of the most common problems in diabetic patients is atherosclerotic cardiovascular disease which is induced by hyperlipidemia. impaired lipid metabolism resulting from uncontrolled hyperglycemia has been implicated in cardiovascular complications in diabetic patients. also, glycated hemoglobin (hba1c) has been regar...