Glucose-6-phosphate dehydrogenase (G6PD) in humans is an X-chromosome-linked disorder and housekeeping enzyme, vital for the survival of every cell. It catalyses the oxidation of glucose-6-phosphate to 6-phospho gluconate in the first committed step of the pentose phosphate pathway, which provides cells with pentoses and reducing power in the form of NADPH. NADPH is required to protect the cell...

rats. Since lathyrus peas are grown extensively as a forage crop, this problem is important also in animal husbandry. It is evident that the nutrition of the peoples of other continents than our own will become a matter of increasing concern to us in the years ahead. For this reason, it is desirable to understand the nut,ritive value of many foods not commonly used in America. The problems of l...

Motulsky, A. G., and Kampbell-Kraut, J. M. (1961). Population genetics of glucose-6-phosphate-dehydrogenase deficiency of the red cells. Proceedings of Conference on Genetics in Disease, p. 159. Grune and Stratton, New York and London. Shahidi, N. T., and Diamond, L. K. (1959). Enzyme deficiency in erythrocytes in congenital nonspherocytic hemolytic anemia. Pediatrics, 24, 245. Taj-Eldin, S., A...

abstract background: sodium bicarbonate serum therapy is used for compensation bicarbonate lost and increasing blood ph in metabolic acidosis caused by severe anemia in patient with glucose-6-phosphate dehydrogenase (g6pd) deficiency. the aim of present study was comparison the effect of serum therapy using two different serums (serum with bicarbonate and without bicarbonate) on some renal and ...

OBJECTIVE The most important cause of infant mortality during the first month of life is related to congenital abnormalities. Nevertheless, timely diagnosis of these diseases can reduce the severity of their effects. The present study aimed to investigate the cost-effectiveness of the neonatal screening program in Fars Province, Iran. METHODS In this study, costs of executing the screening pr...

G6PD deficiency is a common erythrocyte enzymatic disorder characterized by clinical, biochemical and molecular heterogeneity, being point mutations the most frequently detected genetic defect. Because the G6PD gene is located on the X chromosome, the clinical manifestations of the disease are usually confined to hemizygous men. However, female carriers might also have hemolytic anemia in relat...

T HE SELF-LIMITED NATURE of drug-induced hemolytic crises has been effectively demonstrated by Dern and associates1 in American Negroes, and is believed to be a peculiar feature of primaquine sensitivity. It is well known that gbucose-6-phosphate dehydrogenase-(G-6-PD ) deficient states effect also the Caucasian racial group and particularly the Sardinians among whom 15 per cent are affected.2 ...