نتایج جستجو برای: farahzads cda model

تعداد نتایج: 2106251  

Journal: :Planetary and Space Science 2006

Journal: :AMIA ... Annual Symposium proceedings. AMIA Symposium 2012
Sondra R. Renly Rita Altamore Sarah Quaynor Lisa Nelson Kendall Patterson John T. E. Timm Anna Orlova Lori Reed-Fourquet

Clinical Document Architecture implementation guides (IGs) specify a standard format for electronic submission and are typically developed by a few standards specialists working in national committees that do not have the resources to address the range of use cases needed for community-wide document-based health information exchange. To accommodate the variation inherent in these use cases we m...

Journal: :Cancer research 1999
E Månsson T Spasokoukotskaja J Sällström S Eriksson F Albertioni

2F-Adenine arabinoside (fludarabine, Fara-A) and 2-chloro-2'-deoxyadenosine (cladribine, CdA) are nucleoside analogues with antineoplastic activity in vitro and in vivo. Lack of clinical resistance between CdA and Fara-A has been demonstrated in patients with chronic lymphocytic leukemia (G. Juliusson et al., N. Engl. J. Med., 327: 1056-1061, 1992). To clarify the differences in mechanism of re...

Journal: :The Journal of clinical investigation 1984
J H Galla D N Bonduris S L Dumbauld R G Luke

To determine whether chloride-depletion metabolic alkalosis (CDA) can be corrected by provision of chloride without volume expansion or intranephronal redistribution of fluid reabsorption, CDA was produced in Sprague-Dawley rats by peritoneal dialysis against 0.15 M NaHCO3; controls (CON) were dialyzed against Ringer's bicarbonate. Animals were infused with isotonic solutions containing the sam...

Journal: :Gastroenterology 2017
Edwin Liu Fran Dong Anna E Barón Iman Taki Jill M Norris Brigitte I Frohnert Edward J Hoffenberg Marian Rewers

BACKGROUND & AIMS Little is known about the incidence of celiac disease in the general population of children in the United States. We aimed to estimate the cumulative incidence of celiac disease in adolescents born in the Denver metropolitan area. METHODS We collected data on HLA-DR, DQ genotypes of 31,766 infants, born from 1993 through 2004 at St. Joseph's Hospital in Denver, from the Diab...

2017
Yuxin Zhao Xiong Deng Shaoqing Zhang Zhengyu Liu Chang Liu Gabriel Vecchi Guijun Han Xinrong Wu

Climate signals are the results of interactions of multiple time scale media such as the atmosphere and ocean in the 15 coupled earth system. Coupled data assimilation (CDA) pursues balanced and coherent climate analysis and prediction initialization by incorporating observations from multiple media into a coupled model. In practice, an observational time window (OTW) is usually used to collect...

Journal: :Haematologica 1998
I Callea G Console G Sculli M Filangeri G Messina F Morabito

Combinations of different drug concentrations of CLB + FAMP and CLB + 2-CDA were synergistic in, respectively, 42.9% and 34.8%. At leukemic cell survival < or = 50%, 16.4% and 23.4% of all combinations were synergistic in the 2-CDA and FAMP groups, respectively. A significantly higher mean value of antagonistic interactions was observed in the 2-CDA group (p = 0.037).

Journal: :Blood 2013
Achille Iolascon Hermann Heimpel Anders Wahlin Hannah Tamary

The congenital dyserythropoietic anemias (CDAs) are hereditary disorders characterized by distinct morphologic abnormalities of marrow erythroblasts. The unveiling of the genes mutated in the major CDA subgroups (I-CDAN1 and II-SEC23B) has now been completed with the recent identification of the CDA III gene (KIF23). KIF23 encodes mitotic kinesin-like protein 1, which plays a critical role in c...

Journal: :Blood 2000
T Robak J Z Bloński M Kasznicki M Blasińska-Morawiec E Krykowski A Dmoszyńska H Mrugala-Spiewak A B Skotnicki W Nowak L Konopka B Ceglarek S Maj J Dwilewicz-Trojaczek A Hellmann I Urasiński B Zdziarska S Kotlarek-Haus S Potoczek P Grieb

The efficacy and toxicity of cladribine (2-CdA) + prednisone (P) versus chlorambucil (Chl) + P were compared in previously untreated patients with progressive or symptomatic chronic lymphocytic leukemia (CLL) in a randomized, multicenter prospective trial. Eligible patients were assigned to either 2-CdA 0.12 mg/kg per day in 2-hour infusions and P 30 mg/m(2) per day for 5 consecutive days or Ch...

Journal: :The Journal of clinical investigation 1985
A G Togias R M Naclerio D Proud J E Fish N F Adkinson A Kagey-Sobotka P S Norman L M Lichtenstein

The purpose of our study was to assess the effect of cold, dry air (CDA) on the nasal mucosa of selected individuals in relation to the release of inflammatory mediators associated with mast cells. 12 subjects with a history of nasal symptoms of rhinorrhea and congestion upon cold or dry environmental exposure were challenged by nasal breathing of CDA and warm, moist air (WMA). Each subject was...

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