The design of drugs with bioinformatics methods to identify proteins and peptides with a specific toxic action is increasingly recurrent. Here, we identify toxic proteins towards the influenza A virus subtype H1N1 located at the UniProt database. Our quantitative structure-activity relationship (QSAR) approach is based on the analysis of the linear peptide sequence with the so-called Polarity I...

It is obvious that lead intake is of concern not for its beneficial/essential effects on metabolism, but rather for its toxic actions, which can be especially damaging to children. The objective of this study was to analyze the concentration of lead in milk of mothers during prolonged lactation. Milk samples from 43 mothers were collected at 2 months postpartum. Lead was analyzed using atomic a...

Predicate-action diagrams, which are similar to standard state-transition diagrams, are precisely defined as formulas of TLA (the Temporal Logic of Actions). We explain how these diagrams can be used to describe aspects of a specification—and those descriptions then proved correct— even when the complete specification cannot be written as a diagram. We also use the diagrams to illustrate proofs...

Robust statistical methods are important to the evaluation of toxicological interactions (i.e., departures from additivity) among chemicals in a mixture. However, different concepts of joint toxic action as applied to the statistical analysis of chemical mixture toxicology data or as used in environmental risk assessment often appear to conflict with one another. A unifying approach for applica...

Over the past two decades sociology, including sociology of family and personal life, has seen a ‘relational turn’ with growing body work seeking to explain ‘social’ by taking social relations as primary object sociological analyses. Relational sociologies theorise in terms either inter-actions or trans-actions. Inter-actions are that bring separate entities together, while trans-actions posit ...

background: one of the essential aspects of the provision of care is cultural issues. cultural sensitivity is the key for cultural care. the aim of this study was to explore culturally sensitive care in pediatric nursing care in iran.materials and methods: this study was a conventional content analysis. participants were consisted of 25 nurses and 9 parents selected through purposive sampling f...