Recent studies suggest that subcortical structures, including striatum, are vulnerable to amyloid-b accumulation and other neuropathological features in familial Alzheimer’s disease due to autosomal dominant mutations. We explored differences between familial and sporadic Alzheimer’s disease that might shed light on their respective pathogenic mechanisms. To this end, we analysed 12 brain regio...

We report a familial case of keratoconus with corneal granular dystrophy. The mother and first son have both keratoconus and corneal granular dystrophy and the second son has keratoconus alone. The keratoconus in this family is thought to be an autosomal dominant or an X-linked inheritance pattern. Granular dystrophy is an autosomal dominant inheritance. This familial case suggests that the gen...

The familial association of pulmonary stenosis, atrial septal defect, and unique electrocardiographic abnormalities involving a mother and two children is reported. Familial pulmonary stenosis not occurring as part of a named syndrome or without associated multiple congenital abnormalities is rare. The constellation of pulmonary stenosis, atrial septal defect, and the particular electrocardiogr...

An underlying factor with the problems of trip making in urban areas is related to land use potentials and condition its transport system. The pattern any settlement basis for physical planning, especially rapidly growing cities. This study examines households’ selected cities Osun State, Nigeria. Data were obtained uses. also randomly from 2,134 households examine their pattern. Descriptive st...

This paper proposes a new fuzzy similarity measure to calculate the degree of similarity of generalized fuzzy numbers (GFN’s).The fuzzy similarity measure is developed by integrating the concept of centre of gravity (COG) points and fuzzy difference of distance of points of fuzzy numbers. A fuzzy description for difference of distances between fuzzy numbers in its turn exploits appropriate simi...

extended abstract introduction zanjan has recently enjoyed considerable population and physical growth. the rapid irregular growth in population number caused unfavorable formation of informal settlement areas in the city. islamabad is of the largest informal accommodation regions in zanjan which was built as a consequence of massive rural migration during 1970s. although the area, at present,...

The ability of agent-based models (ABMs) to represent heterogeneity in the characteristics and behaviors of actors enables analyses about the implications of this heterogeneity for system behavior. The importance of heterogeneity in the specification of ABMs, however, creates new demands for empirical support. An earlier analysis of a survey of residential preferences within southeastern Michig...

Recently, Kitaev [Ki2] introduced partially ordered generalized patterns (POGPs) in the symmetric group, which further generalize the generalized permutation patterns introduced by Babson and Steingŕımsson [BS]. A POGP p is a GP some of whose letters are incomparable. In this paper, we study the generating functions (g.f.) for the number of k-ary words avoiding some POGPs. We give analogues, ex...

This research elucidates the trip pattern of the low-density residential zone in a semi-urban industrial cluster of southwestern Nigeria. These sets of dwellers are often times neglected in the transportation planning process with the view that it is not a residential zone. Domiciliary information gathering procedure was employed in the analysis with 0.82 return rates. It was backed up with the...