INTRODUCTION Severe malaria due to P. vivax infection is increasingly observed now a days. Organ failure in vivax malaria is caused by mechanisms of inflammation as well as sequestration. In this study we have compared the complications in vivax malaria with those in falciparum or mixed malaria. AIMS AND OBJECTIVES 1) To study various complications in adult inpatients of vivax malaria. 2) To ...

Abstract 
 Background: the most prevalent and pathogenic malaria parasite associated with severe illness death is Plasmodium falciparum. In non-endemic countries like Russian federation, P. falciparum a relatively rare but potentially fatal disease found in travelers returning from high burden.
 Aims: this review aims to analyze recommendations for managing different World Health Orga...

background: pfmdr1 and its variants are molecular marker which are responsible for antibiotics resistance in plasmodium falciparum, a parasitic carrier for malaria dis-ease. a novel strategy to treat malaria disease is by disrupting parasite lactate dehy-drogenase (pldh), a crucial enzyme for plasmodium survival during their erythro-cytic stages. this research was aimed to investigate and chara...

background: falciparum malaria is a severe health burden worldwide. antigen presenting cells are reported to be affected by erythrocytic stage of the parasite. malarial hemozoin (hz), a metabolite of malaria parasite, has adjuvant properties and may play a role in the induction of immune response against the parasite. objective: to determine the immunological impact of hemozoin on the capacity ...

This study investigated alterations in platelet counts pre- and post-treatment with artemisinin derivatives in uncomplicated and severe falciparum malaria. Serial platelet counts were taken over 4 weeks for 110 uncomplicated and 110 severe falciparum malaria patients admitted to the Hospital for Tropical Diseases during 2005-2008. On admission, prior to treatment, thrombocytopenia was found in ...

In recent years, rapid diagnostic tests (RDTs) have been widely used for malaria detection, primarily because of their simple operation, fast results, and straightforward interpretation. The Asan EasyTest™ Malaria Pf/Pan Ag is one of the most commonly used malaria RDTs in several countries, including Korea and India. In this study, we tested the diagnostic performance of this RDT in Uganda to e...

The disease now known as malaria was described as early as 2700 B.C. In the twenty-first century, this disease remains a leading cause of morbidity and mortality. WHO statistics estimate that to date there were 214 million cases of malaria and 438000 deaths in 2015 [1]. While five Plasmodium species can cause malaria in humans, Plasmodium, vivax and P. falciparum are the predominant species in ...

BACKGROUND & OBJECTIVES Description of severe vivax malaria and mixed species infection requires good clinical study. The present study was undertaken to evalute the characteristics of severe malaria patients in Bikaner, northwest India. METHODS This prospective study included 539 admitted adult patients of severe malaria (Plasmodium falciparum 274, P. vivax 221, and mixed infection of Pv + P...

Severe falciparum malaria is common in tropics, patients usually present with any of the following manifestations or combination of cerebral manifestations, circulatory failure, liver failure, acute lung injury and acute kidney injury. Pulmonary manifestations in falciparum malaria usually include acute respiratory distress syndrome (ARDS) and acute lung injury (ALI)1. Here, we present two case...

The development of rapid and specific diagnostic tests to identify individuals infected with malaria is of paramount importance in efforts to control the severe public health impact of this disease. This study evaluated the ability of a newly developed rapid malaria diagnostic test, OptiMAL (Flow Inc., Portland, Oreg.), to detect Plasmodium vivax and Plasmodium falciparum malaria during an outb...