Accepted goals of heart failure treatment include: 1) improvement in symptom status, 2) prevention of disease progression, and 3) reduction in morbidity and mortality (1). Complex pharmacologic therapies achieve these goals for many, but not all, patients with heart failure. For patients who remain symptomatic despite receiving “optimal” medical therapy, novel adjunctive therapies are needed. T...

Appropriate spatial scales of hydrological variables were determined using an existing methodology based on a balance in uncertainties from model inputs and parameters extended with a criterion based on a maximum model output uncertainty. The original methodology uses different relationships between scales and variable statistics. It is extended with two different uncertainty propagation method...

Recognizing the challenges that a contemporary university faces, an inter-faculty group of researchers performed the analysis of organizational and management approach in one of Russia’s universities and modeled existing business processes. The university is a multi-campus organization and to manage it efficiently it is necessary to make transition from the traditional management model to a mor...

Acceptance and Commitment Therapy (ACT) is a new development within behavioral therapy. Its goal is to promote psychological flexibility. Numerous studies show that suffering results when people attempt to avoid their inner experiences (experiential avoidance). This experiential avoidance often leads to rigid and inflexible behavior that also leads them to compromise their goals and what is imp...

Methodical planning for formulating sustainability policy is needed to meet the ambitious United Nations Sustainable Development Goals (SDGs). This paper proposes an approach such low-income nations by systematically dividing principal into manageable categories. These categories encompass all 17 SDGs, enabling policymakers take account complex interlinkages of SDGs planning. Key actions that n...

We analyze a little-studied regulatory approach that we call “management-based regulation.” Management-based regulation directs regulated organizations to engage in a planning process that aims toward the achievement of public goals, offering firms flexibility in how they achieve public goals. In this paper we develop a framework for assessing conditions for using management-based regulation as...

Effective interventions exist for many priority health problems in low income countries; prices are falling, and funds are increasing. However, progress towards agreed health goals remains slow. There is increasing consensus that stronger health systems are key to achieving improved health outcomes. There is much less agreement on quite how to strengthen them. Part of the challenge is to get ex...