INTRODUCTION Hemophilia B is an inherited X chromosome-linked disorder characterized by impaired blood clotting owing to the absence of functional coagulation factor IX. Due to the relatively short half-life of factor IX, patients with hemophilia B require frequent factor IX infusions to maintain prophylaxis. We have developed a recombinant factor IX (rFIX) fused to the Fc region of IgG (rFIXFc...

In an examination of the psychometric characteristics of violent drug abusers, Clinical Analysis Questionnaire (CAQ) profiles were obtained from a population of incarcerated male offenders who had committed homicide under chronic psychostimulant influence. They were abstinent at time of assessment. Comparison of the profiles of twenty-nine previous chronic cocaine abusers with nine previous met...

The amplitude of an EMG and the temporal pattern can be used when considering if an EMG profile is normal or not. In the method described in this paper a gain factor of the complete EMG profile was determined and then the profile normalised with this gain factor. This normalised individual profile was then compared with a standard profile, predicted on the basis of walking speed. Deviating prof...

In this study, the Brownian motion and thermophoresis effects on the MHD ferrofluid flow over a cone with thermal radiation were discussed. Kerosene with the magnetic nanoparticles (Fe3O4) was considered. A set of transformed governing nonlinear coupled ordinary differential equations were solved numerically using Runge-Kutta based shooting technique. A simulation was performed by mixing ferrou...

The purpose of present research work is to develop gastro retentive formulation for Moxifloxacin using various release retardants. Moxifloxacin, novel synthetic fluoro quinolone, antibacterial agent. Floating tablets of Moxifloxacin. HCl were prepared using variable amounts of HPMCK4M, HPMCK15M and HPMCK100M with effervescent mixtures by direct compression technique. Totally 9 formulations were...

background: multiple sclerosis (ms) is one of the most prevalent of nerves system disease. ms is a chronic neurodegenerative disorder. nutrition and diet are effective factors for prevention and treatment in ms, however finding are controversial. the aim of this study was investigation of dietary pattern of fat consumption and its relationship with lipid profiles crp level in ms patient.  metho...