With ever-growing amounts of omics data, the next challenge in biological research is the integration and interpretation of these data to gain mechanistic insights about cellular function. Protein–protein and protein–DNA interaction networks served for over a decade as the workhorses behind those interpretation efforts, but their use was limited to topologically based observations. Specifically...

Simulation projects are usually cooperative endeavors that involve not only the work on the simulation model itself but also a lot of communication among project partners. In the past, support for communication and cooperation in simulation projects has been poor to non-existent. The Web Based Simulation Center is designed to bring simulation and cooperation together. Because this approach requ...

The US Family Smoking Prevention and Tobacco Control Act and WHO Framework Convention on Tobacco Control provide us with powerful tools to reduce the death and disease caused by the use of tobacco products. One tool that can contribute substantially toward this goal is the authority to establish performance standards for tobacco products. Conjointly with reducing levels of nicotine in cigarette...

higher education plays a very vital role in developing human resources as well as economic ones in every country. in so doing, the act of evaluation would help the decision makers as well as managers to spot the weaknesses to use the required provisions to work more effectively. the present study with a different approach toward the designing a comprehensive evaluation expert system using fuzzy...

The issue of the failure of incumbent firms in the face of radical technical change has been a central question in the technology strategy domain for some time. We add to prior contributions by highlighting the role a firm’s existing set of complementary assets have in influencing its investment in alternative technological trajectories. We develop an analytical model that considers firm hetero...

Clients with HIV infection have been conceptualized as a vulnerable population. Although some researchers have examined vulnerability with clients with HIV infection, a theory of vulnerability in the context of HIV infection is non-existent. The purpose of this study was to describe, using qualitative methodology, the process by which vulnerability occurs in the context of HIV infection. Ground...

Epithelioid sarcoma (ES) is a soft tissue sarcoma of children and young adults for which the preferred treatment for localized disease is wide surgical resection. Medical management is to a great extent undefined, and therefore for patients with regional and distal metastases, the development of targeted therapies is greatly desired. In this review, we will summarize clinically relevant biomark...

In the present study, we investigated gender-related effects on road safety attitudes in 2681 young drivers (1458 males, 54.4%; aged 18-22) who filled out several scales assessing attitudes toward road safety issues, driving behavior in specific hypothetical situations, accident risk perception, and concerns about such a risk. We focused only on young drivers to better understand the role of ge...

Core values are critical to an organization’s identity, mission, strategy, and success. Harmonizing personal the core espoused by organization addresses congruence gaps ensures that actions of employees consistent aligned with organizational strategies. This study aims identify HR management practices a University in Manila, Philippines promote between organization. The qualitative research met...