objectives: to determine the characteristics and etiologies of occupational trauma associated mortality in tabriz megacity, northern iran. methods : in a cross-sectional study, we included all the recorded cases of occupational mortalities referring to tabriz forensic medicine center, labor institute and imam reza and sina hospitals between march 2011 and march 2012. we recorded the demographic...

the occurrence of neonatal seizures may be the first and perhaps, the only clinical sign of a central nervous system (cns) disorder in the newborn infant. identifying the etiology for the neonatal seizures is/critical to prognosis and treatment. the most common etiology for neonatal seizures is hypoxic-ischemic encephalopathy. seizures may indicate the presence of a potentially treatable etiolo...

BACKGROUND Prostate cancer incidence and mortality rates in South Korea are relatively low, but rising steadily. METHODS We examined age-standardized incidence and mortality trends of prostate cancer in South Korea to gain further insight into prostate cancer etiology. RESULTS Although prostate cancer incidence has been low (7.9 per 100,000 man-years), it has increased up to 28.2% between 1...

Network pharmacology is an emerging technique, which integrates systems biology and computational biology to study multi-component and multi-targeted formulations. Ayurveda, the traditional system of Indian medicine, uses intelligent formulations; however, their scientific rationale and mechanisms remain largely unexplored. This paper presents the potential of network pharmacology to understand...

Tobacco use remains one of the greatest challenges to global health and is accepted as a major contributor to the rise in cancer incidence and mortality in the past century. Despite substantial knowledge about the harms conferred by tobacco in its various forms, recent changes in tobacco product development, marketing, and usage have changed the landscape in which tobacco research is operating....

Pancreatic cancer is the fourth leading cause of cancer deaths and is characterized by dismal prognosis. Xenograft and genetically engineered mouse (GEM) models have recapitulated critical elements of human pancreatic cancer, providing useful tools to probe the underlying cause of cancer etiology. In this review, we provide a brief description of the common genetic lesions that occur during the...

To the Editor: Mammographic density and ethnicity are two of a handful of factors very strongly associated with breast cancer risk, the others being major genetic influences and age (due to accumulation of somatic mutations). Genetic influences aside, levels of endocrine factors implicated in breast cancer etiology would be expected to be positively associated with mammographic density and be h...

The hypothesis that diet and related metabolic, anthropometric and hormonal factors could play a role in cancer etiology was originally supported by a series of early case-control studies, geographical correlation studies (also called ecological studies) (NRC 1982) as well as pioneering work on rodents in experimental laboratory studies carried out in the 1940s (Tannenbaum 1940a, 1940b, 1942a a...