ABSTRACT The recent interstellar detection of cyanonaphthalenes brings interest in related aromatic molecular species that could be present similar astronomical environments. In this context, ethynyl derivatives naphthalene are promising candidates to observed the Taurus Molecular Cloud (TMC-1), where together with cyano- and ethynyl-derivatives cyclopentadiene benzene have been detected. To en...

Experimental For the synthesis of: Sodium 2'-(Dicyclohexylphosphanyl)-2,6-diisopropyl-(1,1-biphenyl)-4-sulfonate (sXPhos) 12 4 Standard Reaction Procedure of 5-bromoindole 15 under reflux: 5 Microwave Reaction Procedure of 5-bromoindole 15: 5 Standard Microwave Reaction Procedure for Tryptophans: 5 (S)-2-Amino-3-(5-(phenylethynyl)-1H-indol-3-yl)propanoic acid 19 6 (S)-2-Amino-3-5-((3-fluorophen...

This study examined how the 1199G > A polymorphism in the ABCB1 gene encoding P-glycoprotein (P-gp) affects the protein's expression, ATPase activity, and ability to pump female steroid sex hormones out of LLC-PK1 cells. The ABCB1 (1199G) or ABCB1 (1199A) allele was transfected into cells, which were incubated for 48 h with various hormone concentrations, then analyzed by Western blotting to ex...

The intrinsic acidity of CH2[double bond, length as m-dash]CHXH2, HC[triple bond, length as m-dash]CXH2 (X = N, P, As, Sb) derivatives and of their complexes with BeH2 and BH3 has been investigated by means of high-level density functional theory and molecular orbital ab initio calculations, using as a reference the ethyl saturated analogues. The acidity of the free systems steadily increases d...

Considerable attention has recently been focused on environmental chemicals that disrupt the reproductive system by altering steroid receptor function. Although numerous in vitro and in vivo methods have been shown to be useful approaches for identifying chemicals that can disrupt reproduction through a direct interaction with the estrogen receptor, it is imperative that the protocols selected ...

qct calculations were performed to study the behavior of energized nh2oh formed by association collision of nh2 radical with oh radical. a potential energy surface that describes the behavior of the title reaction has been constructed by interpolation of ab initio data. h2o, hon, hno, nh3, o, h2no, cis or trans-honh, and h products and two vibrationally energized nh2oh and nh3o adducts were obs...

Organosilicon molecules such as silicon carbide (SiC), dicarbide (c-SiC2), tricarbide (c-SiC3), and tetracarbide (SiC4) represent basic molecular building blocks connected to the growth of silicon-carbide dust grains in outflow circumstellar envelopes carbon-rich asymptotic giant branch (AGB) stars. Yet, fundamental mechanisms formation carbides early processes that initiate coupling silicon–ca...

We report the detection for first time in space of three new pure hydrocarbon cycles TMC-1: c -C 3 HCCH (ethynyl cyclopropenylidene), 5 H 6 (cyclopentadiene), and 9 8 (indene). derive a column density 3.1 × 10 11 cm −2 cycle similar values, range (1−2) 13 , second third. This means that cyclopentadiene indene, spite their large size, are exceptionally abundant, only factor five less abundant th...

Because of its unique electronic properties, o-carborane has attracted attention as a scaffold for constructing solid-state luminescent materials. Here, we report stimulus-responsive luminochromic materials based on polycyclic aromatic hydrocarbon (PAH), such anthracene and pyrene, modified with the ethynyl-o-carborane unit. Initially, luminochromism originating from switching different emissio...

Fine structures of 8-G-1-(p-YC(6)H(4)C identical with CSe)C(10)H(6) [1 (G = H) and 2 (G = Cl): Y = H (a), OMe (b), Me (c), F (d), Cl (e), CN (f), and NO(2) (g)] are determined by the X-ray analysis. Structures of 1, 2, and 3 (G = Br) are called A if each Se-C(sp) bond is perpendicular to the naphthyl plane, whereas they are B when the bond is placed on the plane. Structures are observed as A fo...