The major objectives of this study were i) to evaluate the permeability and swelling characteristics of isolated films prepared by mixing of pectin with ethylcellulose; and ii) to assess the absorption and in vitro/in vivo correlation (IVIVC) of 5-FU film-coated colon-targeted pellets in dogs. Free films were prepared by casting and solvent evaporation method. These free films were evaluated by...

Glaucoma is a second leading cause of blindness globally after cataract, which is managed through eye drops, which are highly inefficient due to a low bioavailability of less than 1-5%. Frequent administration of eye drops leads to incompliance in patients, so there is a great need for medical device such as contact lenses to treat glaucoma. The objective of research was to provide sustained oc...