The effect of ethanol feeding on the essential fatty acid content of tissues has been contradictory. To define the effect, we analyzed fatty acid profiles in various tissues from five miniature pigs fed daily 105 kJ basal diet/kg body wt and 146 kJ ethanol/kg body wt, and also five control pigs pair-fed the same amount of basal diet but with corn starch substituted for ethanol. After 12 mo, bio...

Acrylic acid (AA) is used widely in the synthesis of esters essential in the production of paints, adhesives, plastics, and coatings. The minimal systemic toxicity of AA is attributed to its rapid oxidation to acetyl-CoA and CO2 via the vitamin B12-independent beta-oxidation pathway. This oxidation is localized to the mitochondria and preliminary evidence suggests a possible inhibition of mitoc...

Acrylic acid (AA) is used widely in the synthesis of esters essential in the production of paints, adhesives, plastics, and coatings. The minimal systemic toxicity of AA is attributed to its rapid oxidation to acetyl-CoA and CO2 via the vitamin B12-independent beta-oxidation pathway. This oxidation is localized to the mitochondria and preliminary evidence suggests a possible inhibition of mitoc...

The aim of this study was to investigate the effect incorporating black soldier fly (BSF) larvae and its processed form as an alternative source protein fish meal on digestibility amino acids (AA) in weaned pigs. Four cannulated pigs with initial bodyweight 13.25 ± 0.25 kg aged 30 days were subjected a 4 × Latin square design three treatments, well nitrogen-free treatment. diets used for each t...

Fibulin-4 is an extracellular matrix protein that is essential for proper assembly of arterial elastic fibers. Mutations in fibulin-4 cause cutis laxa with thoracic aortic aneurysms (TAAs). Sixty percent of TAAs occur in the ascending aorta (AA). Newborn mice lacking fibulin-4 (Fbln4(-/-)) have aneurysms in the AA, but narrowing in the descending aorta (DA), and are a unique model to investigat...

Betaine and conjugated linoleic acid (CLA) may improve pig performance increase lean mass, but the mechanisms are not well understood. Gastrointestinal tract, pancreas, spleen mesenteric fat comprise portal-drained viscera (PDV). Nutrient energy availability of productive tissues be compromised by PDV because its anatomical situation elevated oxygen consumption. The objective this study was to ...

Platelet-derived growth factors (PDGFs) play important roles in skeletal development and bone fracture healing, yet how PDGFs execute their functions remains incompletely understood. Here we show that PDGF-AA, but not -AB or -BB, could activate the BMP-Smad1/5/8 pathway in mesenchymal stem cells (MSCs), which requires BMPRIA as well as PDGFRα. PDGF-AA promotes MSC osteogenic differentiation thr...

A novel algorithmic method for weaving design is presented, inspired by the recently discovered AA Fractals. The method is capable of producing a weaving pattern from any binary sequence or pair of sequences. All generated patterns can be woven in the simplest (4-shaft) dobby looms. An algorithm for generating input binary sequences is also presented, and the sequences produced by this algorith...

Numerous groups have documented that Ascorbic Acid (AA) promotes cardiomyocyte differentiation from both mouse and human ESCs and iPSCs. AA is now considered indispensable for the routine production of hPSC-cardiomyocytes (CMs) using defined media; however, the mechanisms involved with the inductive process are poorly understood. Using a genetically modified mouse embryonic stem cell (mESC) lin...