A 37-year-old female presented to the hospital with erythema migrans and fatigue developed hypotension and variable episodes of AV block, including both Mobitz I and complete AV block. She was treated with IV antibiotics and her arrhythmia resolved within 24 hours without any further intervention.

In an initial experiment, culture-grown Borrelia burgdorferi was added to freshly collected uninfected human blood. This in vitro study demonstrated that more spirochetes were distributed into the plasma than into the serum fraction. In a subsequent clinical study, B. burgdorferi was recovered from plasma cultures of approximately 50% of 42 patients with early Lyme disease associated with eryth...

Lyme serology was positive for both IgG and IgM (ELISA, Enzygnost Borreliosis , Siemens, Dade Behring, Germany, and blot, Euroline WB , Euroimmun, Germany). A punch biopsy of a papule showed a dermal perifollicular ( fig. 2 ) – and occasionnally perineural – infiltrate of lymphocytes and plasma cells, consistent with a borrelial infection. Borrelia burgdorferi DNA was amplified from fresh tissu...

The AA describe the first italian case of Lyme Disease in a middle aged woman: the patient developed after a tick bite the classical erythema chronicum migrans lesions and one month later an oligoarthritis. By indirect immunofluorescence assay it has been found a significant titre compatible with an infection by Borrelia burgdorferi, the causative agent of Lyme Disease.

Improved surveillance indicates that Lyme borreliosis, an emerging zoonosis in the United Kingdom, has increased from 0.06/100,000 during 1986-1992 to 0.32/100,000 since 1996. Case reports peaked in the third quarter of each year. Several high-incidence localities were identified. Erythema migrans was reported in 41% of patients; arthritis in 4%; musculoskeletal symptoms in 18%; and neuroborrel...

Borrelia burgdorferi sensu stricto is a causative agent of human Lyme borreliosis in the United States and Europe. We report here the completed genome sequences of strain B31 isolated from a tick in the United States and two closely related strains from Europe, PAli and PAbe, which were isolated from patients with erythema migrans and neuroborreliosis, respectively.

BACKGROUND Public health authorities in Quebec have responded to the progressive emergence of Lyme disease (LD) with surveillance activities and education for family physicians (FPs) who are key actors in both vigilance and case management. OBJECTIVES To describe FPs' clinical experience with LD, their degree of knowledge, and their practices in two areas, one with known infected tick populat...