The Biopharmaceutics Classification System (BCS) was developed for prediction of in vivo pharmacokinetic performance of drug products from measurements of permeability and solubility. If the permeability criteria changed with metabolism criteria than it may be useful in predicting overall drug disposition, including routes of drug elimination and the effects of efflux and absorptive transporter...

An extensively tacit understandings of equivalency between the deformed HeisenbergWeyl algebra in noncommutative space and the undeformed Heisenberg-Weyl algebra in commutative space is elucidated. Equivalency conditions between two algebras are clarified. It is explored that the deformed algebra related to the undeformed one by a non-orthogonal similarity transformation. Furthermore, non-exist...

The gas-phase structures of the disilanes 1,1,2,2-tetrakis(trimethylsilyl)disilane [(Me3Si)2HSiSiH(SiMe3)2] (1) and 1,1,2,2-tetrakis(trimethylsilyl)dimethyldisilane [(Me3Si)2MeSiSiMe(SiMe3)2] (2) have been determined by density functional theoretical calculations and by gas electron diffraction (GED) employing the SARACEN method. For each of 1 and 2 DFT calculations revealed four C2-symmetric c...

This paper addresses a new method of constructing Korean-Chinese verb patterns from existing patterns. A verb pattern is a subcategorization frame of a predicate extended by translation information. Korean-Chinese verb patterns are invaluable linguistic resources that only used for Korean-Chinese transfer but also for Korean parsing. Usually a verb pattern has been either hand-coded by expert l...

Montague grammar [5] provides a good framework for a direct translation from a natural language sentence into its logical formulas. This is enabled by the fact that every syntactic rule has its corresponding translation rule. As soon as a subphrase is recognized by a syntactic rule, its corresponding translation rule translates the recognized subphrase into its logical formula. M-grammar of Lan...

Abstract The objective of this study was to assess the regulatory framework for health data in Indonesia order understand policy context and explore possibility expanding adoption implementation FAIR Guidelines, which state that should be Findable, Accessible, Interoperable Reusable (FAIR), Indonesia. Although Guidelines were not explicitly mentioned any documents relevant Indonesian digital se...

Obtaining a biowaiver for topical drugs used in veterinary species faces many of the same challenges associated with human topicals. However, the skin of domestic animals varies anatomically and biochemically and experimental approaches to assess bioequivalence (BE) in veterinary species have challenges that are not often encountered with human skin. This is especially the situation with locall...