In many epidemiologic studies, investigators have reported an inverse relation between nonsteroidal antiinflammatory drugs (NSAIDs) and colon cancer, but fewer researchers have examined the relation with gastric cancer. Cases for this study consisted of incident gastric adenocarcinomas (n = 643) identified between 1993 and 2004 among members of the Multiethnic Cohort (Hawaii and Los Angeles, Ca...

Low maternal education is consistently associated with increased risk of preterm delivery (PTD). The interpregnancy interval (IPI), defined as the time between the date of a previous birth and the conception date of the index pregnancy, may mediate this relationship. We estimated controlled direct effects to assess whether hypothetical interventions designed to increase IPIs would reduce the ed...

The Physician Payment Review Commission has examined the potential of profiling physician practice patPR. Lee and A.B. Bindman, Institute for Healty Policy Studies, University of California, San Francisco. P.R. Lee, D.W. Shapiro and R.D. Lasker, Physician Payment Review Commission. A.B. Bindman, Division of General Internal Medicine, San Francisco General Hospital. terns within the context oi c...

Keywords sports medicine, evidence-based regression analysis, effect modifier, epidemiologic, mediation analysis

Selenium is a trace mineral that plays a role in antioxidant defenses as a component of glutathione peroxidase. Epidemiologic findings on the relation of selenium status to risk of heart disease are inconsistent. Therefore, the authors investigated prospectively the association between toenail selenium levels and risk of coronary heart disease (CHD) in a case-control study nested within the Hea...

BACKGROUND Several epidemiologic studies have reported an inverse association between serum levels of carotenoids and cardiovascular disease risk. However, no studies have reported an association between serum carotenoids and N-terminal pro-brain-type natriuretic peptide (NT-proBNP) in the general population. METHODS In this cross-sectional study, we investigated whether serum carotenoids wer...

Prospective associations between quantity and frequency of alcohol consumption and cancer-specific mortality were studied using a nationally representative sample with pooled data from the 1988, 1990, 1991, and 1997-2004 administrations of the National Health Interview Survey (n = 323,354). By 2006, 8,362 participants had died of cancer. Cox proportional hazards regression was used to estimate ...

One of the neglected soil and/or food-borne diseases with international public health importance is toxocariasis. Human cases are being increasingly reported from Asian, African, Oceania, European and the American countries. Hence, human toxocariasis (HT) is now considered as a major zoonosis with global and regional importance. In Iran, human and animal toxocariasis is an endemic disease with ...

Epidemiology can be considered as a very old science. For example, John Graunt, a statistician, published Natural and Political Observations. In the Bills of Mortality in 1662, he analyzed the mortality rolls in London before the Great Plague, presented one of the first life tables, and reported time trends for many diseases. He provided statist...