Background: Epicardial adipose tissue (EAT) is a visceral fat depot with unique anatomic, biomolecular and genetic features. Due to its proximity the coronary arteries myocardium, dysfunctional EAT may contribute development progression of cardiovascular metabolic-related adiposity-based chronic diseases. The aim this work was describe, by morphological techniques, early origin EAT. Methods: ad...

Intrathoracic lipotoxicity is the consequence of increased accumulation and biological activity of various fat deposits in obesity, more specifically epicardial (“fat around the heart”) and intramyocardial fat (“fat within the myocardium”). Epicardial fat is located in close proximity to the coronary arteries within the visceral pericardial layer (in contrast to the paracardial or mediastinal f...

Coronary perivascular adipose tissue (PVAT) is a visceral adipose tissue of mesothelial origin that normally surrounds the major coronary arteries on the surface of the heart. Coronary PVAT is functionally distinct from the adipose tissue found on the surface of the myocardium, which is defined as myocardial epicardial adipose tissue. In addition to adipocytes and preadipocytes, coronary PVAT c...

Abstract Background and aim Obesity is associated with an increase in different adipose depots. The anatomic distribution of internal confers risks. Recently, significant interest has emerged the expansion epicardial tissue (EAT) as a mediator adverse cardiovascular events. Often, post-mortem examination remains best method investigating morphological changes health disease. This study aimed to...