نتایج جستجو برای: epc و pml
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قرارداد طراحی، تهیه تجهیزات و ساخت (epc)، یکی از قراردادهای شایع جهان امروز است. هنگامی که بخش دولتی تمایل دارد که از تخصص پیمانکاران خصوصی داخلی یا خارجی در طراحی و ساخت پروژه های زیربنایی استفاده کند، قراردادها epc را قالب حقوقی مناسب می یابد. در این مقاله کوشیده ایم تا به مهم ترین جنبه های حقوقی این دسته قراردادها از قبیل ساختار قرارداد epc، رابطه حقوقی طرفین قرارداد، ضمانت نامه ها، مسوولیت ...
صلاخلا ـ ة : ُّ دعتُ ل ثم ةيعيبطلا تاغللا ةجلاعم تاقيبطت نم ديدعلل ايساسأ انوكم ةيعوضوملا ةئزجتلا قيبطت تامولعملا عاجرتساو صوصنلا صيخلت . نم فدهلا وه ثحبلا اذ ه قت و مي ةيعوضوملا ة ئزجتلا تا يمزراوخ ة يلاعف ضوملا دودحلا ى لع فرعتلا يف ة يبرعلا صوصنلا لخاد ةيعو . م تو قايس لا اذ ه يف ة فلتخم رداصم نم ةيبرع صوصن ةسمخ لخاد اهنوظحلاي يتلا ةركفلا وأ عوضوملا تاريغت ىلع فرعتلل ةيبرعلا ةغللا ءارق نم ة...
To deal with ambiguities in partial multi-label learning (PML), existing popular PML research attempts to perform disambiguation by direct ground-truth label identification. However, these approaches can be easily misled noisy false-positive labels the iteration of updating model parameter and latent variables. When labeling information is ambiguous, we should depend more on underlying structur...
ةصلاخلا Allopeas gracilis is recorded for the first time in southern Iraq. It was collected from two localities (Abu-Al Khaseeb region and Hareer region) from Basrah city. ضرلاا عقوقلا نم ةنيع نورشعو نامث ي Allopeas gracilis مت للاخ ةرصبلا ةنيدم ،ريرح ةقطنم و بيصخلا وبا ةقطنم نم اھعمج ناسين رھش 2008 راذاو 2008 يلاوتلا ىلع . ليجستلا اذھ ربتعي دعب ةرصبلا ةنيدم نم ةيضرلاا عقاوقلا نم ثلاثلا Monacha...
Introduction: Chronic lymphocytic leukemia (CLL) is the most frequent leukemia in adults living in Western countries. with a diverse clinical course that due to life expectancy less than two years between patients finding ,new therapeutic strategies is essential for it. Curcumin as the biologic active of turmeric, has many biological properties such as anti-inflammatory, anti-oxidant, anti-diab...
PML protein plays important roles in regulating cellular homeostasis. It forms PML nuclear bodies (PML-NBs) that act like nuclear relay stations and participate in many cellular functions. In this study, we have examined the proteome of mouse embryonic fibroblasts (MEFs) derived from normal (PML(+/+)) and PML knockout (PML(-/-)) mice. The aim was to identify proteins that were differentially ex...
Promyelocytic leukemia (PML) has been implicated in a variety of functions, including control of TP53 function and modulation of cellular senescence. Sumolated PML is the organizer of mature PML bodies, recruiting a variety of proteins onto these nuclear domains. The PML gene is predicted to encode a variety of protein isoforms. Overexpression of only one of them, PML-IV, promotes senescence in...
Promyelocytic leukemia protein PML acts as a tumor suppressor, while its chimeric mutant PML/RARα causes acute promyelocytic leukemia (APL). Because PML has been shown to form transcription-regulatory complexes with various molecules, we speculated that PML and/or PML/RARα might affect STAT3 activity, which plays a crucial role in G-CSF-induced growth and survival of myeloid cells. In luciferas...
Hanan Selman Hessan and Ahmed Mohammed Abbas 563 Abstract Immune status was examined after tonsillectomy operations in 30 children with recurrent acute tonsillitis, their ages ranged between 3-10 years, were clinically diagnosed by ENT surgeon at AlHilla General Teaching Hospital and 10 apparently healthy children were included as a control in the study which lasted from February to May 2011 .I...
Promyelocytic leukemia nuclear bodies (PML-NBs) are PML-based nuclear structures that regulate various cellular processes. SUMOylation, the process of covalently conjugating small ubiquitin-like modifiers (SUMOs), is required for both the formation and the disruption of PML-NBs. However, detailed mechanisms of how SUMOylation regulates these processes remain unknown. Here we report that SUMO5, ...
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