To explore age-related mechanisms in the expression of recurrent headache, we evaluated whether genetic and environmental influences are a function of the reporting age using questionnaire information that was gathered in 1973 for 15- to 47-year-old Swedish twins (n = 12,606 twin pairs). Liability to mixed headache (mild migraine and tension-type headache) was explained by non-additive genetic ...

Changes in the mean and variance of gene expression with age have consequences for healthy aging and disease development. Age-dependent changes in phenotypic variance have been associated with a decline in regulatory functions leading to increase in disease risk. Here, we investigate age-related mean and variance changes in gene expression measured by RNA-seq of fat, skin, whole blood and deriv...

Random regression models (RRM) have become common for the analysis of longitudinal data or repeated records on individual over time. The goal of this paper was to explore the use of random regression models with orthogonal / Legendre polynomials (RRL) to analyze new repeated measures called clutch size (CS) as a meristic trait for Iranian native fowl. Legendre polynomial functions of increasing...

1. The genetical and environmental structure of covariation between finger ridge counts in twin and sibling data has been analysed using the method of Martin and Eaves (1977) adapted from Jöreskog. 2. The model for environmental covariance contains a single factor loading on all ten digits but most environmental variance is specific to each finger. 3. For additive genetic variance there is one ...

the selection of high yielding varieties with good stability‏ ‏is an important objective in rice breeding ‎programs. the grain yield of eight rice lines with a check (nemat) were compared‎‏ ‏on six locations of gilan ‎and mazandaran provinces during two years, using rcbd with four replications. combined analysis of ‎variance showed that the effect of variety and year ‎‏×‏‎ location ‎‏×‏‎ variet...

BACKGROUND Twin and family studies that estimated the heritability of daily physical activity have been limited by poor measurement quality and a small sample size. OBJECTIVE We examined the heritability of daily physical activity and sedentary behavior assessed objectively by using combined heart rate and movement sensing in a large twin study. DESIGN Physical activity traits were assessed...

We performed a large-scale experiment on the effects of inbreeding and population bottlenecks on the additive genetic and environmental variance for morphological traits in Drosophila melanogaster. Fifty-two inbred lines were created from the progeny of single pairs, and 90 parent-offspring families on average were measured in each of these lines for six wing size and shape traits, as well as 1...

size from birth to 5 years in a population-based twin cohort were studied. Sex differences in gene–environment etiology were also explored. Analyses used data from the Quebec Newborn Twin Study (QNTS), a population-based birth cohort of 672 twin pairs. The final sample consisted of 177 complete twin pairs. Heritability of weight was moderate at birth while common environmental factors accounted...

We study the problem of finding probability densities that match given European call option prices. To allow prior information about such a density to be taken into account, we generalise the algorithm presented in Neri and Schneider (Appl. Math. Finance 2013) to find the maximum entropy density of an asset price to the relative entropy case. This is applied to study the impact of the choice of...

Records on final BW (kg), backfat depth (cm), and LM area (cm(2)) of pigs from a University of Nebraska Large White/Landrace composite population were analyzed to estimate the effects of pen mates. Measurements were at approximately 180 d of age for 3,524 pigs in 351 pens (9 to 11 pigs per pen) farrowed from 1999 to 2005. The area of each pen was 8.13 m(2). The full model (M1) included the fixe...