BACKGROUND/AIMS Endonasal endoscopic surgery continues to gain acceptance as a minimally invasive, effective approach for benign and malignant pathology of the paranasal sinuses and skull base. Postoperative epistaxis could potentially result in rapid and devastating consequences due to hemorrhage. Our objective was to assess the incidence and causes of epistaxis after endoscopic skull base sur...

Abstract Objective Our objective was to compare the long-term outcomes of endoscopic resection versus open surgery in combination with radiotherapy for locally advanced sinonasal malignancies (SNMs). Methods Data continuous patients squamous cell carcinoma and adenocarcinoma who received (endoscopic or surgery) combined our center between January 1999 December 2016 were retrospectively reviewed...

Objectives The endoscopic technique in transnasal skull base surgery offers optimal visualization and free manipulation in the surgical field. However, it may cause approach-related sinonasal injury, influencing patients' quality of life (QOL). To minimize rhinological morbidity without restrictions in surgical manipulation and tumor resection, we introduced the unilateral transethmoidal-parase...

Introduction: Magnetic resonance imaging (MRI) provides information about tumor size and extension, infiltration of major blood vessels nerves, early bone-marrow infiltration, lymph node involvement. Transnasal endoscopic approaches are an integral part the therapeutic arsenal developed to address malignant sinonasal skull-base neoplasms. Objective: To analyze use magnetic in diagnosis perineur...

OBJECTIVE To study the expression of important elements of the innate immune responses in human sinonasal tissue to elucidate its potential role in mucosal inflammation. DESIGN We studied human sinonasal tissue from patients with chronic rhinosinusitis and an immortalized epithelial cell line to detect the expression of innate immune effectors and the responses of these cells to stimulation w...

OBJECTIVE To evaluate the oncologic outcomes of patients with sinonasal cancer treated with endoscopic resection. DESIGN Retrospective review. SETTING Tertiary care academic cancer center. PATIENTS All patients with biopsy-proved malignant neoplasm of the sinonasal region who were treated with endoscopic resection between 1992 and 2007 were included in the study, and their charts were rev...

BACKGROUND Inverted papilloma (IP) is a benign tumor of the nasal cavity and paranasal sinuses first described by Ward in 1854. IP is remarkable due to a high propensity for tumor recurrence with incomplete resection, potential for invasion of local structures, and an association with malignant transformation to squamous cell carcinoma. Surgery is the mainstay of treatment for sinonasal IP, and...

inverted papillomas of the nose and paranasal sinuses are uncommon neoplasms, characterized by their tendency to occur and by their association with malignancy. in the past decade there has been a trend toward the use of endoscopic surgical techniques in the management of these tumors. this article presents the results of a prospective study of24 patients with inverted papilloma resected by the...

Objectives To describe the presentation, work-up, and management of patients with metastatic renal cell carcinoma (RCC) to the sinonasal cavity and skull base, and to describe our current treatment algorithm of endoscopic surgical resection followed by radiation therapy. Design Retrospective review of two recent cases from our institution over a 1-year period, with a relevant review of the lite...