Protein and mRNA levels of heat-labile enterotoxin (LT) of Escherichia coli are highest at 37 degrees C, and they decrease gradually as temperature is decreased. This temperature effect is eliminated in an Hns- mutant. Deletion of portions of DNA coding for the LT A subunit also results in an increase in LT expression at low temperatures, suggesting that the H-NS protein causes inhibition of tr...

Diversity is a powerful means to increase the transmission performance of wireless communications. For the case of fountain codes relaying, it has been shown previously that introducing diversity is also beneficial since it counteracts transmission losses on the channel. Instead of simply hop-by-hop forwarding information, each sensor node diversifies the information flow using XOR combinations...

Familial cerebral cavernous malformations type III (fCCM3) is a disease of the cerebrovascular system caused by loss-of-function mutations in ccm3 that result in dilated capillary beds that are susceptible to hemorrhage. Before hemorrhage, fCCM3 lesions are characterized by a hyperpermeable blood-brain barrier (BBB), the key pathologic feature of fCCM3. We demonstrate that connexin 43 (Cx43), a...

The trophic linkage between yellow perch Perca flavescens and two exotic prey items, alewife Alosa pseudoharengus and round goby Neogobius melanostomus, was investigated in the extreme southern area of Lake Michigan during the summer of 2002. Yellow perch 100mm total length, LT (n1⁄4 1293) exhibited size selective feeding, with 148 fish containing round gobies and 120 fish containing alewives. ...

Cytokeratin (CK)-18 is the major intermediate filament protein in the liver and during hepatocyte apoptosis is cleaved by the action of caspases; the resulting fragments are released into the blood as caspase-cleaved cytokeratin (CCCK)-18. Higher circulating levels of CCCK-18 have been found in patients with hepatocellular carcinoma (HCC) than in healthy controls and than in cirrhotic patients....

Abstract The impact of combined addition high levels bismuth up to 120 wt ppm and cerium 2000 on the graphite morphology in GJS 450-18 with 3.2 wt% carbon silicon was studied. Experiments were conducted insulated keel blocks a solidification time 40 min. Samples from thermal centre castings analysed by optical microscopy, forms sizes particles characterised. Bismuth addition, even at 25 ppm, re...

Connexin26 (Cx26) and connexin30 (Cx30) are two major protein subunits that co-assemble to form gap junctions (GJs) in the cochlea. Mutations in either one of them are the major cause of non-syndromic prelingual deafness in humans. Because the mechanisms of cochlear pathogenesis caused by Cx mutations are unclear, we investigated effects of Cx30 null mutation on GJ-mediated ionic and metabolic ...

Gap junctions (GJs)-mediated intercellular communications (GJICs) are connexin (Cx)-formed plasma membrane channels that allow for the passage of small molecules between adjacent cells, and are involved in several physiopathological processes, including immune responses against cancer. In general, tumor cells are poorly coupled through GJs, mainly due to low Cx expression or reduced channel act...