High-frequency spectroscopy has been applied to monitoring the stability of oil-in-water emulsions. It was found that stable emulsions showed absorption peaks at around 550 MHz; further, they shifted from lower to higher frequencies with time. The rate of increase of the frequencies was dependent on the amount of emulsifier added. These results show that the stability of emulsions can be monito...

The review focused on technique of solid self-emulsifying pellets (SEPs) for solubility enhancement poorly water soluble drug. oral route administration has been and still is currently the primary drug delivery owing to its potential advantages compared other routes. process hydrophobic drugs plays a key role in formulation development achieve bioavailability therapeutic action at target site.1...

Approximately 40 % of newly discovered chemical entities have low solubility and possess bioavailability after oral administration. Lipid-based drug delivery systems (LBDDS) recently become very popular because their remarkable ability to deliver drugs with poor absorption using lipids as carriers. Self-emulsifying (SEDDS) are one type LBDDS employed for the incorporation hydrophobic drugs. SED...

Surfactants are amphipathic molecules constituted by hydrophobic and hydrophilic regions that usually get distributed on interfaces between fluid phases of different polarities (water/oil and oil/water) [1]. Several compounds with tensoactive properties are synthetized by living organisms (animals, plants and microorganisms), being considered natural surfactants or biosurfactants, which reduce ...