BACKGROUND Cough on emergence has been reported as a common adverse reaction with sugammadex reversal. We investigated if staggering the dose of sugammadex will reduce emergence cough in a single-center, randomized, double-blinded study. METHODS A hundred and twenty ASA 1-3 adults were randomly reversed with 1 mg/kg sugammadex prior to extubation followed by another 1 mg/kg immediately after ...

OBJECTIVE Investigating the behavioral and cognitive effect of memantine in moderate to severe patients with Alzheimer's disease receiving donepezil. MATERIAL AND METHOD 43 patients were enrolled in this prospective, randomized, parallel group study. There were no significant imbalances between the treatment groups in demographic and baseline clinical characteristics. Cognitive and global mea...

BACKGROUND Emergence agitation, vomiting, and oculocardiac reflex (OCR) in children undergoing strabismus surgery under general anesthesia are common problems. The purpose of this study was to determine whether the effect of analgesia can reduce the incidence of these problems. We compared the effects of sub-Tenon's injection versus intravenous (IV) and rectal paracetamol in this surgery. MET...

background: the present study was aimed to evaluate the efficacy of acetaminophen plus dexamethasone on post‑operative emergence agitation in pediatric adenotonsillectomy. methods: a total of 128 patients were randomized and assigned among four groups as: intravenous (iv) dexamethasone, oral acetaminophen, iv dexamethasone plus oral acetaminophen, placebo. group 1 received 0.2 mg/kg dexamethaso...