BACKGROUND Identification of serum proteins that track with disease course in sarcoidosis may have clinical and pathologic importance. We previously identified up-regulated transcripts for interferon-inducible chemokines CXCL9, and CXCL10, in blood of sarcoidosis patients compared to controls. The objective of this study was to determine whether proteins encoded by these transcripts were elevat...

Methods Fifteen year old sibling 1 presented with history of low grade fevers since 2 months, oral ulcers, malar rash, alopecia, pallor, arthralgia, history of loss of weight and appetite. Investigations revealed anaemia, leukopenia, high ESR, and low C3, C4 levels. She also had ANA +ve 1: 1280, ds DNA +ve, lupus anticoagulant +ve, anticardiolipin antibody +ve, normal urine protein creatinine r...

INTRODUCTION Spondylodiscitis (SD) is an uncommon but important infection. The aim of this work was to study the risk factors, bacteriological features, clinical, laboratory and radiological findings of SD, and to shed light on the initial treatment. METHODOLOGY A total of 107 patients who underwent treatment for SD were evaluated. The diagnosis of SD was defined by clinical findings, complet...

Background Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are most commonly employed acute phase reactants in follow up of patients with Familial Mediterranean Fever (FMF). As a rule CRP increases during FMF attacks but it returns to normal values in attack free periods. Persistently elevated acute phase reactants in attack free periods can be occasionally observed in patient...

Monoclonal Gammopathy of Undetermined Significance (MGUS) is one the plasma cell dyscrasias. An isolated finding a monoclonal para-protein in serum or urine hallmark MGUS. Most often it found incidentally during an unrelated medical evaluation and/or investigation to find cause for neuropathy, anaemia, rashes, vasculitis elevated Erythrocyte Sedimentation Rate (ESR). This case report illustrate...

Background: The combined index of fibrinogen and neutrophil-lymphocyte ratio (F-NLR) has recently been reported as a new predictive factor in patients with cancer. However, the NLR have not simultaneously evaluated rheumatoid arthritis (RA). Objectives: This study aimed to explore clinical value F-NLR RA its relationship disease activity. Methods: retrospective collected 143 82 age- gender-matc...

Osteoarthritis (OA) is the most common articular disease world wide. It is the result of both mechanical and biological events that destabilize the normal coupling of degeneration synthesis of articular cartilage and subchondral bone. Rheumatologist often routinely order tests for rheumatoid factor and erythrocyte sedimentation rate (ESR) for all patients with joint complaints as well as C reac...

OBJECTIVE In this study, we aimed to determine the urinary levels of pyridinium cross-links and urinary beta-isomerized fragments derived from the C-telopeptide of the alpha1 chain of type I collagen (beta-CTX) as markers of bone resorption in patients with ankylosing spondylitis (AS), and to study their relationship to markers of disease activity [erythrocyte sedimentation rate (ESR)] and to d...