Electrospun fiber scaffolds has made a huge progress in tissue engineering applications owing to their continuous morphology with variable chemical, physical, and biological properties. In this review paper, we reviewed the electrospinning technique, its processing parameters characterizations involved. A focus on shape memory poly (glycerol sebacate) (PGS)-based electrospun for field was explo...

Periodontitis is a widespread dental disease affecting 10 to 15% of worldwide adult population, yet the current treatments are far from satisfactory. The human periodontal ligament stem cell is a promising potential seed cell population type in cell-based therapy and tissue regeneration, which require appropriate scaffold to provide a mimic extracellular matrix. Zein, a native protein derived f...

background: the aim of this study was to fabricate the poly caprolactone (pcl) aligned nanofiber scaffold and to evaluate the survival, adhesion, proliferation, and differentiation of rat hair follicle stem cells (hfsc) in the graft material using electrospun pcl nanofiber scaffold for tissue engineering applications. methods: the bulge region of rat whisker was isolated and cultured in dmem: n...

UNLABELLED Burn injuries in the United States account for over one million hospital admissions per year, with treatment estimated at four billion dollars. Of severe burn patients, 30-90% will develop hypertrophic scars (HSc). In this study, we evaluate the impact of an elastomeric, randomly-oriented biostable polyurethane (PU) scaffold on HSc-related outcomes. In vitro, fibroblast-seeded PU sca...

aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (pcl), poly (vinyl alcohol) (pva) and hydroxyapatite nanoparticles (nha). the morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...

In this work we propose a new method titled "layered hydrospinning." In this method, nanofibers are being collected on top of a liquid reservoir and assembled layer-by-layer to form a 3D scaffold. The geometrical features of fabricated hydrospun scaffolds show a porosity of 99% and pores of a diameter over 100 microm. Cells were seeded during the hydrospinning process, thus achieving an initial...

Electrospinning has been recognized as an efficient technique for the fabrication of polymernanofibers. Recently, various polymers have successfully been electrospun into ultrafine fibers.Electrospinning is an extremely promising method for the preparation of tissue engineering scaffolds.In this study, nanofibers gelatin was electrospun at 20% v/v optimized content. To produce...

The purpose of this study was to achieve a sustained release of hydrophilic l-ascorbic acid 2-phosphate magnesium (ASP) from electrospun polycaprolactone (PCL) scaffolds, so as to promote the osteogenic differentiation of stem cells for bone tissue engineering (TE). ASP was loaded and electrospun together with PCL via three electrospinning techniques, i.e., coaxial, emulsion, and blend electros...

Electrospun nanocomposite scaffolds were fabricated by encapsulating multi-walled carbon nanotubes (MWNT) in poly (lactic acid) (PLA) nanofibers. Scanning electron microscopy (SEM) confirmed the fabrication of nanofibers, and transmission electron microscopy identified the alignment and dispersion of MWNT along the axis of the fibers. Tensile testing showed an increase in the tensile modulus fo...

Tissue engineering techniques using a combination of polymeric scaffolds and cells represent a promising approach for nerve regeneration. We fabricated electrospun scaffolds by blending of Poly (3-hydroxybutyrate) (PHB) and Poly (3-hydroxy butyrate-co-3- hydroxyvalerate) (PHBV) in different compositions in order to investigate their potential for the regeneration of the myelinic membrane. The t...