The retina and brain share similar neurochemistry neurodevelopmental origins, with the retina, often viewed as a “window to brain.” With retinal measures of structure function becoming easier obtain in clinical populations there is growing interest using findings potential biomarkers for disorders affecting central nervous system. Functional biomarkers, such electroretinogram, show promise neur...

For more than a century, Dutch scientists and clinicians have contributed importantly to the understanding of cardiac electrophysiology and to the diagnosis and treatment of cardiac rhythm disturbances. The first example supporting this statement that comes to mind is the development of a string galvanometer and the registration of the human electrocardiogram by Willem Einthoven in 1901 [1]. Al...

Cell-Type-Specific Electrophysiology In article number 2103564, Namsun Chou, Il-Joo Cho, and co-workers develop a multimodal multi-shank fluorescence neural probe system. The enables combined electro-optical recordings for cell-type-specific electrophysiology from multiple deep-brain regions at high spatiotemporal resolution. system gives new experimental paradigm to enable the precise investig...

Electrical measurements from large populations of animals would help reveal fundamental properties of the nervous system and neurological diseases. Small invertebrates are ideal for these large-scale studies; however, patch-clamp electrophysiology in microscopic animals typically requires invasive dissections and is low-throughput. To overcome these limitations, we present nano-SPEARs: suspende...