Abstract Due to their position in the pulmonary mucosa, CD8 +tissue resident memory T cells (T RM) act as sentinels that rapidly respond to, and mediate protection against, respiratory viruses. In mice, RMhave been shown at barrier sites by producing cytokines, chemokines, performing cell lysis. However, humans, less is known about effector functions of virus-specific lung +T RM. Using from hea...

The development of cancer vaccines is based on the premise that tumor cells are potentially targetable by host immunity through effective presentation tumor-associated antigens to reactive T-cell populations. Vaccine efficacy may be limited functional properties effector including lack high-affinity T target self-antigens. In contrast, neoantigens arise from tumor-specific mutational events gen...

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Thi s puper eztcn,ds the caging theory of R i m o n and Bluke [ill for. orre-parameter two-finger grippers t o orwparame tar three-finger grippers. T h e caging theory describes lroui the f ingers of a robot gripper can be placed uroumd u n object so tha t it cannot escape. A s the fiingers close f r o m such a configuration, the f reedom of the object t o move is gradually restricted, unti l ,...

We present a planner for a robot to keep an object stable under a sequence of external forces. We assume a robot with multiple manipulators, with a gripper at the end of each manipulator. We make two key contributions: First, given an external force, we propose a method to check the feasibility of gripper placements on the object to resist the force. This method takes into account both the mani...

ANALYSIS OF SPHERICAL FIVE-BAR HINGED MANIPULATOR WITH TWO DEGREES OF FREEDOM AND DWELLS OF OUTPUT LINK. N. Davitashvili. “Problems of Mechanics”. Tbilisi, 2015, No 1(58), pp. 5-11, (Engl.). Is stated the kinematic study of spherical five-bar manipulator with two degrees of freedom. Are determined the positions, velocities and accelerations of output links, their points and gripper. The manipul...

The paper presents an optimal synthesis of overconstrained linkages, based on the factorization of rational curves contained in Study’s quadric. The group of Euclidean displacements is embedded in a affine space where a metric between motions based on the homogeneous mass distribution of the end effector is used to evolve the curves such that they are fitted to a set of target poses. In the end...

Bent and folded beam configurations have been popularly used in electrothermoelastic (E-T) actuation. This paper introduces new designs of thermal end-effector with micro-grasping and micro-heating capabilities. We obtained analytical models for all possible steady state temperature responses of suspended and overhanging microstructures that constitute bent beam, folded beam, and combined actua...