Cells of a V79 subline of the Chinese hamster were microirradiated at wavelength 365 nm in the presence of the psoralen derivative, trioxsalen. Microirradiation was accomplished by a pulsed argon laser microbeam either in anaphase or in interphase 3 hr after mitosis. Inhibition of clonal growth and formation of micronuclei at the first postirradiation mitosis were observed after microirradiatio...

Simulations of gas-solid fluidized beds have been performed using a hybrid simulation method, which couples the discrete element method (DEM) for particle dynamics with the averaged two-fluid (TF) continuum equations for the gas phase. The coupling between the two phases is modeled using an interphase momentum transfer term. The results of the hybrid TF-DEM simulations are compared to experimen...

The method described in the present work was assessed through the production of composite materials made of polypropylene reinforced with chemical thermomechanical pulp of hemp core fibers. Composite materials were obtained by extrusion and injection molding, and by the addition of a coupling agent to ensure a good interphase between fiber and matrix. In all cases, the composite materials were ...

Statistica1 thermodynamics of martensitic transformation is developed in the frame of the self-consistent field approximation. The accommodation mechanisms of the parent phase to the martensitic variant growth are described by the three order parameters. The latters reflect the concentration and the orientation of the martensitic phase and the dislocation density at the interphase boundaries. S...

The influence of viscoelastic thermal compression (VTC) of wood on bonding performance was studied. Mode-II (shear mode) fracture of the bonded interphase was performed using the overnotched and end-notched flexure methods. The study examined four groups of specimens; a control and VTC specimens with three different degrees of densification (63, 98, and 132%). The specimens were bonded with phe...

Particle-polymer nanocomposites often exhibit mechanical properties described poorly by micromechanical models that include only the particle and matrix phases. Existence of an interfacial region between the particle and matrix, or interphase, has been posited and indirectly demonstrated to account for this effect. Here, we present a straightforward analytical approach to estimate effective ela...

In interphase HeLa cells, incubation with histamine or thapsigargin led to the rapid release of arachidonic acid. The release was absolutely dependent on Ca2+, consistent with the activation of an 85 kDa cytosolic phospholipase A2 (cPLA2). In metaphase-arrested HeLa cells, by contrast, the stimulation of arachidonate release by these agents was inhibited by more than 90%. The lack of arachidoni...

BACKGROUND/PURPOSE Percutaneous permeation is a frequently used approach in drug delivery, but the detailed physics process in the patch--stratum corneum (SC)--viable epidermis system remains unclear: the influence of the interphases in the multilayered structure has been little studied. METHODS This paper applied the finite-element method to develop a contact algorithm with an interphase ele...