BACKGROUND AND OBJECTIVE COPD patients with community-acquired pneumonia (CAP) have worse clinical outcomes, as compared to those without COPD. Cardiovascular disease (CVD) is a common comorbidity for COPD patients. Whether COPD with comorbid CVD will increase the risk of CAP is not well investigated. The incidence and factors associated with CAP in COPD patients with and without CVD were analy...

Breed-wise standard echocardiographic values in dogs have been reported as there is variation in body and chest conformation which limits the application of data of one breed for other breed. Labrador Retrievers being originated from hunting dogs, might have different echocardiographic values from standard normal range of other dog breeds. So, the present study was aimed to determine the M-mode...

Serum leucine-aminopeptidase (LAP) and cystine-aminopeptidase (CAP) determinations have been made using a chemical method based on enzymatic hydrolysis of l-leucine-/?-naphthylamide-hydrochloride and cystine-di-/?naphthylamide, respectively. Fractionation of serum proteins by gel filtration on "Sephadex-G 200" has been used for separation of LAP and CAP (oxytocinase). — CAP which appears during...

The Klebsiella aerogenes hutUH operon is preceded by a promoter region, hut(P), that contains two divergent promoters (hutUp and Pc) which overlap and are alternately expressed. In the absence of the catabolite gene activator protein-cyclic AMP (CAP-cAMP) complex, Pc is predominantly expressed while hutUp is largely repressed. CAP-cAMP has the dual effect of repressing transcription from Pc whi...

BACKGROUND Community-acquired pneumonia (CAP) is frequently associated with the very young and the elderly but is a largely underrecognized burden among working-age adults. Although the burden of CAP among the elderly has been established, there are limited data on the economic burden of CAP in the employed population. OBJECTIVE To assess the economic impact of CAP in US working-age adults fr...

BACKGROUND The role of mixed pneumonia (virus+bacteria) in community-acquired pneumonia (CAP) has been described in recent years. However, it is not known whether the systemic inflammatory profile is different compared to monomicrobial CAP. We wanted to investigate this profile of mixed viral-bacterial infection and to compare it to monomicrobial bacterial or viral CAP. METHODS We measured ba...

Prevention of implant-associated infections has been one of the main challenges in orthopaedic surgery. This challenge is further complicated by the concern over the development of antibiotic resistance as a result of using traditional antibiotics for infection prophylaxis. The objective of this study was to develop a technique that enables the loading and local delivery of a unique group of ca...

case presentation we present a case with a typical picture of myocarditis but normal echocardiographic findings, the diagnosis of which was confirmed by cardiac mri. discussion in particular, cardiac mri data are useful in borderline cases or in the presence of discrepancy between clinical picture and echocardiographic results. introduction the diagnosis of myocarditis based on a spectrum of fi...

Previously we reported that calcium phosphate nanoparticles (CAP) represented a superior alternative to alum adjuvants in mice immunized with viral protein. Additionally, we showed that CAP was safe and elicited no detectable immunoglobulin E (IgE) response. In this study, we demonstrated that following mucosal delivery of herpes simplex virus type 2 (HSV-2) antigen with CAP, CAP adjuvant enhan...

BACKGROUND We hypothesized that obstructive sleep apnea (OSA) can predispose individuals to lower airway infections and community-acquired pneumonia (CAP) due to upper airway microaspiration. This study evaluated the association between OSA and CAP. METHODS We performed a case-control study that included 82 patients with CAP and 41 patients with other infections (control group). The controls ...