background and objective: to estimate the risk of human papilloma virus (hpv) infection for cervical malignancies, we conducted a case-control study in southern iran (hormozgan province). materials and methods: for this purpose,52 paraffin embedded blocks with exact diagnosis of cervical carcinoma(50 carcinomas and 2 carcinomas in situ) from 2001 to 2006 and 52 praffin embedded blocks of cervic...

Bovine papilloma antigen detected by fluorescent antibody was correlated with the appearance of infectious virus and with epithelial hyperplasia and hyperkeratinization in the developing bovine cutaneous papilloma. Neither antigen nor infectious virus was found in the earliest stages of growth characterized by connective tissue pro liferation and by little or no epithelial change. The cellular ...

Abstract Sarcoid tumors were described by means of histopathological and molecular procedures in a 5-year-old donkey. Histopathological examination showed epithelial changes including hyperkeratosis, hyperplasia, koilocytosis, rete peg formation. Neoplastic fibroblastic cells plumb, large spindle to stellate embedded dense collagenous tissue. Results Polymerase Chain Reaction DNA sequence analy...

BACKGROUND Nearly 20% of human cancers worldwide have an infectious etiology with the most prominent examples being hepatitis B and C virus-associated hepatocellular carcinoma and human papilloma virus-associated cervical cancer. There is an urgent need to find new approaches to treatment and prevention of virus-associated cancers. METHODOLOGY/PRINCIPAL FINDINGS Viral antigens have not been p...

Cutaneous beta-papillomaviruses are associated with non-melanoma skin cancers that arise in patients who suffer from a rare genetic disorder, Epidermodysplasia verruciformis (EV) or after immunosuppression following organ transplantation. Recent studies have shown that the E6 proteins of the cancer associated beta human papillomavirus (HPV) 5 and HPV8 inhibit NOTCH and TGF-β signaling. However,...

Oral squamous papilloma is a benign epithelial tumor that constitutes around 2.5% of all oral verruco-papillary lesions and caused by the Human Papilloma Virus (HPV). HPV subtypes 6 11, which are considered to be low carcinogenic potential usually associated with papilloma. Though there no site predilection as such, most common intraoral sites reported tongue, lips, buccal mucosa, gingiva, pala...

Background: Different studies assessed the role of inflammation in malignancy of different organs. Prostatitis has been suggested as a cause of cancer and BPH. Till now, more than 100 types of human Papilloma virus (HPV) are recognized including low and high-risk groups for carcinogenesis. Among them HPV-16 and HPV-18 have shown further association with cancer. Regarding the pr...

A case of Bowen's disease arising on the medial part of the first metatarsal bone of an 81-year-old Japanese woman is described. Histopathologically, proliferation of atypical cells was found throughout the epidermis. Electronmicroscopy revealed virus particles 40-50 nm in diameter in the nuclei of tumour cells at the granular cells just on or below the horny layer. Positive bands were obtained...