In embryonic chicken liver (ECL) two types of iodothyronine deiodinases are expressed: D1 and D3. D1 catalyzes the activation as well as the inactivation of thyroid hormone by outer and inner ring deiodination, respectively. D3 only catalyzes inner ring deiodination. D1 and D3 have been cloned from mammals and amphibians and shown to contain a selenocysteine (Sec) residue. We characterized chic...

Neurogenesis in the rat hippocampal region was examined with 3R-thymidine autoradiography. The rats in the prenatal groups were the offspring ofpregnant females given two injections oPR-thymidine on consecutive days in an overlapping series: embryonic (E) day E13+E14, E14+E15, ... , E21+E22. The rats in the postnatal (P) groups were injected in two nonoverlapping series: first, the day of birth...

In this paper, we analyze coordination of macroeconomic stabilization policies within the EMU by focusing, in a dynamic set-up, on asymmetries, externalities, and the existence of a multi-country context. We study how coalitions among fiscal and monetary authorities are formed and what are their effects on the stabilization of output and price. In particular, our attention is directed to study ...

Copyright © 1999 American Heart Association. All rights reserved. Print ISSN: 0009-7322. Online 72514 Circulation is published by the American Heart Association. 7272 Greenville Avenue, Dallas, TX 1999;99;17Circulation J. de Feyter and Patrick W. Serruys I. Patrick Kay, Manel Sabate, Jurgen M. R. Ligthart, Willem J. van der Giessen, Pim Coronary Artery Dissection Intracoronary Ultrasound Longit...

We study the properties of generalized stochastic gradient (GSG) learning in forward-looking models. We examine how the conditions for stability of standard stochastic gradient (SG) learning both differ from and are related to E-stability, which governs stability under least squares learning. SG algorithms are sensitive to units of measurement and we show that there is a transformation of varia...

Inactivation of the renin-angiotensin system interferes with the morphogenesis of the renal medulla. Thus ureteric bud (UB) derivatives may be a target for angiotensin production and action. To begin to test this hypothesis, we examined the cellular expression of angiotensinogen (Ao) and AT(1) receptor proteins during rat metanephrogenesis by immunohistochemistry. In addition, we tested whether...

In this study we have characterized the functional expression of T-type Ca(2+) channels in developing chick nodose neurons, a population of placode-derived sensory neurons innervating the heart and various visceral organs. Voltage-gated Ca(2+) currents were measured using whole cell patch clamp recordings in neurons acutely isolated between embryonic day (E) 7 and E20, prior to hatching. E7 nod...

The aim was to demonstrate functional properties of transplanted histologically normal photoreceptors. Subretinal intact-sheet transplants of fetal E17-E20 rat retinas to light-damaged albino rat eyes were fixed in light or dark, 2 to 42 weeks after transplantation, and stained immunohistochemically for certain phototransduction proteins. In light adapted transplants, transducin was predominant...

Developmental shift in GABA actions from depolarization to hyperpolarization occurs as a result of decreasing the intracellular Cl(-) concentration regulated by K(+)-Cl(-) co-transporter 2 (KCC2). To clarify the time-course of the developmental shift on the Purkinje cells, we examined KCC2-localization in the embryonic mouse cerebellum. The KCC2 was first detected within the Purkinje cells in t...