We determined whether human lung fibroblasts (HLFs) might release mediators that are responsible for monocyte chemokinetic activity (MCA) constitutively. HLF supernatant fluids showed MCA in a time-dependent manner ( P < 0.001). Checkerboard analysis of 24- and 72-h supernatant fluids showed that the activity was chemokinetic. Partial characterization of 24- and 72-h supernatant fluids revealed...

the objective of this study was to evaluate kinetics and the residual decline of tylosin in milk and plasma of lactating najdi ewes following single intramuscular injection of tylosin at the dose of 10 mg/kg. blood and milk samples were collected from the ewes before and at different time intervals after treatment. tylosin concentrations were determined by microbiological agar plate assay using...

Little is known about stability of hormones in blood samples stored under various conditions. This study was conducted to examine stability of triiodothyronine (T3), thyroxine (T4), luteinizing hormone (LH), prolactin, insulin, cortisol and progesterone in blood and serum samples. Experiment 1 was designed to determine if concentrations of these hormones were affected by exposure to cellular el...

The objective of this study was to compare, by two experimental methods, the antimicrobial efficacy of different root canal filling pastes used in pediatric dentistry. The tested materials were: Guedes-Pinto paste (GPP), zinc oxide-eugenol paste (OZEP), calcium hydroxide paste (CHP), chloramphenicol + tetracycline + zinc oxide and eugenol paste (CTZP) and Vitapex. Fiven microbial strains (S. au...

BACKGROUND/AIMS To investigate the in vitro effect of a short time exposure to the anthracycline idarubicin on proliferation, protein synthesis, and motility of human Tenon's capsule fibroblasts in comparison with the antitumour antibiotic mitomycin C. METHODS After determination of effective concentrations of idarubicin, fibroblasts of the human Tenon's capsule were exposed to idarubicin or ...

The toxicity of Xanthorrhoea johnsonii methanolic leaf extract was investigated using the Artemia franciscana nauplii bioassay. At 24 h, the extract produced an EC(50) of 361.0 ± 41.8 μg/ml, indicating that it was substantially more toxic than the pesticide Mevinphos (1346.2 ± 80.1 μg/ml) and approximately 4 fold less toxic than potassium dichromate (87.1 ± 5.2 μg/ml). Whilst potassium dichroma...

Liver transplantation (LT) is an established treatment for children with acute and chronic liver failure. Some reports suggest that infants under the age of 1 yr and children weighing under 13 kg are high-risk groups associated with less satisfactory results. This report describes our experience during the pediatric intensive care unit stay of 16 infants weighing <7 kg who received LT. We revie...

Two experiments were conducted to examine the effect of the feeding of a high-energy diet during early gestation on survival of porcine conceptuses. In the first, 91 second-estrus gilts were inseminated 24 h after detection of standing estrus and randomly assigned to a recommended energy (RE: 22.2 MJ of DE/d) or high-energy diet (HE: 36.0 MJ of DE/d) obtained by addition of cornstarch to RE. Gi...

Target drug deliveries using nanotechnology are a novel consideration in the treatment of cancer. We present herein an in vitro mouse model for the preliminary investigation of the efficacy of an iron oxide nanoparticle complex conjugated to vascular endothelial growth factor (VEGF) antibody and ligand cluster of differentiation 80 (CD80) for the purpose of eventual translational applications i...

background: hydatid cysts are formed in human body can be treated clinically by surgery or drugs such as albendazole (abz) and mebendazole (mbz). the purpose of this study was comparing the effects of abz and mbz on glutathione-s-transferase, alkaline phosphatase and protease enzymes activities in protoscoleces of hydatid cyst. methods: the culture supernatants containing the parasite excretory...