Clinical question " Does intramuscular botulinum toxin A injection improve upper-limb function in children with hemiplegic cerebral palsy? " An occupational therapist requested information about the efficacy of botulinum toxin A injection in the upper limb in the light of its success in reducing spasticity and improving gait and range of movement in the lower limb. Search question The patients ...

We have read the case report of Al-Ahmad and Al-Qudah1 regarding the use of botulinum toxin type A in the treatment of masseter hypertrophy, and we agree with the authors when they reported that botulinum toxin type A is an option for patients who declined surgical treatment. However, we would like to make some considerations concerning this type of treatment that can contribute to the authors’...

BACKGROUND Botulinum neurotoxin induces healing in patients with idiopathic fissure. The optimal dosage is not well established. AIM To compare the efficacy and tolerability of two different formulations of type A botulinum neurotoxin, and to provide more evidence with regard to the choice of dosage regimens. METHODS Symptomatic adults with chronic anal fissure were enrolled in a randomized...

The key points to remember about abobotulinumtoxinA are as follows: BoNTA-ABO (abobotulinumtoxinA [Dysport]; Medicis Aesthetics, Scottsdale, AZ) and BoNTA-ONA (onabotulinumtoxin A [Botox Cosmetic]; Allergan, Irvine, CA) are both derivatives of botulinum toxin A produced from different strains of the bacterium Clostridium botulinum through proprietary manufacturing processes, and both are approv...