Christopher A. Lieu1,2, Vikram Shivkumar1, Timothy P. Gilmour1,2, Kala Venkiteswaran1,2, Mark J. Nolt1,3, Milind Deogaonkar4 and Thyagarajan Subramanian1,2 1Department of Neurology, The Pennsylvania State University College of Medicine and M.S. Hershey Medical Center, Hershey, Pennsylvania 2Department of Neural & Behavioral Sciences, The Pennsylvania State University College of Medicine and M.S...

Objective N/A. Background Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a neuroinflammatory disease mediated by antibodies targeting the GluN1 subunit of NMDAR. It presents with well-defined neuropsychiatric symptoms, including psychosis, agitation, seizures, and memory disturbances.1 Movement disorders orofacial dyskinesias are common, but often difficult to manage, no specific pu...

Abstract BACKGROUND Dyskinesias in cancer patients present a diagnostic challenge to clinicians. Etiologies can include paraneoplastic syndromes, chemotherapy related side effects, or primary movement disorders. This is unique case of choreoathetotic dyskinesias patient with metastatic renal cell carcinoma while undergoing treatment cabozantinib combination either placebo the investigational dr...

36 In humans, the control of voluntary movement, in which the cortico-basal-ganglia circuitry 37 participates, is mainly lateralised. However, several studies suggest that both the contralateral 38 and ipsilateral basal ganglia (BG) systems are implicated during unilateral movement. 39 Bilateral improvement of motor signs in Parkinson’s disease patients (PD) has been reported 40 with unilateral...

Levodopa-induced dyskinesias (LID) belong to the most common dose-limiting adverse effects of levodopa therapy. "Peak-dose" LID occur with the maximum effect of medication, 'diphasic dyskinesias' have a "beginning- and end-of-dose" pattern, and the, "off-period dyskinesia" occur during off-periods, most frequently in the early mornings and are typically dystonic in nature. The majority of patie...