A prevalent view of DNA replication has been that it is carried out in fixed "replication factories." By tracking the progression of sister replication forks with respect to genetic loci in live Escherichia coli, we show that at initiation replisomes assemble at replication origins irrespective of where the origins are positioned within the cell. Sister replisomes separate and move to opposite ...

Hepatitis C virus (HCV) infection develops into chronicity in 80% of all patients, characterized by persistent low-level replication. To understand how the virus establishes its tightly controlled intracellular RNA replication cycle, we developed the first detailed mathematical model of the initial dynamic phase of the intracellular HCV RNA replication. We therefore quantitatively measured vira...

Data replication is crucial in enhancing data availability and reducing access latency cloud computing. This paper presents a dynamic duplicate management method for storage systems based on the Inverted Ant Colony Optimization (IACO) algorithm fuzzy logic system. The proposed approach optimizes decisions focusing energy consumption, response time, cost. Extensive simulations demonstrate that I...

Data Grid is a geographically distributed environment that deals with large-scale data-intensive applications. Effective scheduling in Grid can reduce the amount of data transferred among nodes by submitting a job to a node, where most of the requested data files are available. Data replication is another key optimization technique for reducing access latency and managing large data by storing ...

The data grid technology, which uses the scale of the Internet to solve storage limitation for the huge amount of data, has become one of the hot research topics. Recently, data replication strategies have been widely employed in distributed environment to copy frequently accessed data in suitable sites. The primary purposes are shortening distance of file transmission and achieving files from ...

toxoplasmosis is a protozoal infection caused by toxoplasma gondii. toxoplasmosis produce severe damage in patients who are immunosuppresed. in those who are immunosupressed, latent infection can be reactivated resulting in acute disseminating disease. betamethasone is a synthetic glycocorticoid, used as an anti-inflamatory and immunosuppressant in a wide variety of disorders.the aim of this st...

Data Replication is an important aspect to be considered under the cloud and particularly so in the area of data intensive applications. Various replication strategies used in Amazon, Google and Microsoft cloud offerings are discussed followed by comparison of current research scenario and associated algorithms through a suitable tabulation. The merits and gaps existing in these algorithms and ...