Methods Study cohort comprised 50 patients with JIA (34 girls, median age 12.7 and range 7.4-17.4 years, median disease duration 6.3 and range 2.0-15.1 years) previously exposed to systemic glucocorticoids for a minimum of three months (range 0.2-12.5 years). Study protocol included clinical examination, bone age determination, BMD and body composition measurements with dual X-ray absorptiometr...

background: bisphosphonates (bps) are used extensively for managing the osteoporosis. there are some controversies on atypical fractures of femur that associated with increase in cortical thickness (ct) and bps' use. in this study, the effects of alendronate consumption were studied on femoral ct as a predictor for atypical fracture.   methods: forty nine post-menopausal women aged 50-70 years ...

A new approach for computing the atom-in-molecule [quantum theory of atoms in molecule (QTAIM)] energies in Kohn-Sham density-functional theory is presented and tested by computing QTAIM energies for a set of representative molecules. In the new approach, the contribution for the correlation-kinetic energy (T(c)) is computed using the density-functional theory virial relation. Based on our calc...

Assessment of bone mineral density (BMD) by dual-energy x-ray absorptiometry (DXA) plays a vital role in the diagnosis of osteoporosis and in monitoring a patient's response to drug therapy. This commentary will discuss controversies surrounding the use of DXA for screening and monitoring of BMD in women.

Bone density is definitely a bona fide health concern! It?s directly related to the strength of your skeletal frame, which supports your entire body and allows you to move in addition to protecting your soft organs from injury. So, the lower the bone density, the more vulnerable you are to breaks and fractures (more on that later). Bone density tests [2] are administered by health care professi...

Bone density is definitely a bona fide health concern! It?s directly related to the strength of your skeletal frame, which supports your entire body and allows you to move in addition to protecting your soft organs from injury. So, the lower the bone density, the more vulnerable you are to breaks and fractures (more on that later). Bone density tests [2] are administered by health care professi...

In the previous issue of Critical Care, Dr Bellomo and colleagues reported an observational study of the relationship between nutritional intake and survival in the RENAL randomized controlled trial. In summary, the total energy intake in a very large and severely ill patient population was low. Higher average daily caloric energy intake was not associated with improved survival. The study illu...

In this study we investigated the relationship between activity and energy expenditure (EE) in mice. By determining the relationship between activity and EE over a 24 hr period in an individual mouse, activity was calculated to account for 26.6% ± 1.1% of total EE at 30°C. However, when comparing across multiple mice, only 9.53% ± 1.1% of EE from activity appeared to be independent of other com...