BACKGROUND Induction-maintenance therapy is a treatment regime where patients are prescribed an intense course of treatment for a short period of time (the induction phase), followed by a simplified long-term regimen (maintenance). Since induction therapy has a significantly higher chance of pill fatigue than maintenance therapy, patients might take drug holidays during this period. Without gui...

The following definition of resistant hypertension is proposed: Provided that adherence to the regimen can be assured, hypertension should be considered resistant if the blood pressure cannot be reduced to less than 150/100 mm Hg by a rational triple drug regimen, including a diuretic, prescribed in nearly maximal doses and if the pretreatment blood pressure was greater than or equal to 180/115...

BACKGROUND As antiretroviral treatment (ART) programs mature, data on drug utilization and costs are needed to assess durability of treatments and inform program planning. METHODS Children initiating ART were followed up in an observational cohort in Thailand. Treatment histories from 1999 to 2009 were reviewed. Treatment changes were categorized as: drug substitution (within class), switch a...

INTRODUCTION Non-adherence to medical regimen has remained a challenge to the medical profession as well as to social sciences. To achieve positive results, the factors negatively impacting patient adherence to medical regimens (i.e., diet, drug and exercise regimen) must be scrutinized in detail. The objective of this research was to explore the relationship between cognitive appraisal and adh...

Previous reports from the Tuberculosis Chemotherapy Centre, Madras, have established that ambulatory treatment of pulmonary tuberculosis with the combination of isoniazid and PAS, administered daily, yields satisfactory results. However, in the usage of any unsupervised regimen, reliance must be placed on the co-operation of patients in self-administering their drugs. Irregularities in drug-tak...

This paper outlines a treatment protocol to run alongside of standard current treatment of glioblastoma- resection, temozolomide and radiation. The epithelial to mesenchymal transition (EMT) inhibiting sextet, EIS Regimen, uses the ancillary attributes of six older medicines to impede EMT during glioblastoma. EMT is an actively motile, therapy-resisting, low proliferation, transient state that ...

furazolidone (fzd), a nitrofuran derivative, is an antibacterial agent in use by the medical and veterinary fields. the chinese have utilized fzd to relieve stomach pain, 5 years before the discovery of helicobacter pylori. this drug is currently a part of helicobacter pylori's eradication regimen. however, some carcinogenic and toxic adverse effects associated with fzd have been observed in an...