we estimate that there are more than 100000 patients presently on statin treatment, and that about 10% of these patients will also be on long-term warfarin therapy. I believe your Editorial was correct in highlighting the issue of safety, and to suggest that “physicians must tell their patients the truth about rosuvastatin”. However, I would add that physicians themselves should be informed of ...

When a drug is prescribed for a patient with a permanent pacemaker or an implantable cardioverter defibrillator (ICD), consideration must be given to the potential interactions. Drug effect on pacemaker performance is usually thought to cause an increase or decrease in pacing threshold. From a practical view, Class IC drugs must be used cautiously in pacemaker patients, especially in those who ...